Vaginal tumors are neoplasms (tumors) found in the vagina. They can be benign or malignant. ^{[1] [a]} A neoplasm is an abnormal growth of tissue that usually forms a tissue mass. ^{[2] [3] [4]} Vaginal neoplasms may be solid, cystic or of mixed type. ^[5]

Vaginal cancers arise from vaginal tissue, with vaginal sarcomas develop from bone, cartilage, fat, muscle, blood vessels or other connective or supportive tissue. ^{[6] [7]} Tumors in the vagina may also be metastases (malignant tissue that has spread to the vagina from other parts of the body). ^{[8] [7]} Cancer that has spread from the colon, bladder, and stomach is far more common than cancer that originates in the vagina itself. ^[9] Some benign tumors may later progress to become malignant tumors, such as vaginal cancers. ^{[10] [11]} Some neoplastic growths of the vagina are sufficiently rare as to be only described in case studies. ^[3]

Signs and symptoms may include a feeling of pressure, painful intercourse or bleeding. ^[12] Most vaginal tumors are located during a pelvic exam. Ultrasonography, CT and MRI imaging is used to establish the location and presence or absence of fluid in a tumor. ^{[13] [14]} Biopsy provides a more definitive diagnosis. ^[15]

Vaginal tumors

Vaginal tumors	Benign	Synonyms and notes	References
Yolk sac tumor	no	Endodermal sinus tumor	[16] [17] [18] [19] [20] [21] [22]
Peripheral primitive neuroectodermal tumor	no	Ewing's sarcoma	[16] [17] [18] [23]
Vaginal melanoma	no	Melanocytic tumor	[16] [17] [18] [24] [25]
Blue nevus	yes [26]	Melanocytic tumor, blue mole, nevus bleu, melancytic nevus	[16] [17] [18] [25]
Carcinosarcoma	no	Malignant Mullerian Mixed tumors; metaplastic carcinoma	[18]
Sarcoma botryoides	no	botryoid sarcoma, botryoid rhabdomyosarcoma; subtype of embryonal rhabdomyosarcoma	[9] [16] [17] [18] [22] [27] [28]
Leimyosarcoma	no	localized tumor of leukemic cells	[18] [29]
Endometrioid stromal sarcoma	no	endometrial stromal sarcoma	[18] [30]
Undifferentiated vaginal sarcoma			[18]
Leiomyoma	yes	fibromyoma	[6] [13] [16] [17] [18]
Genital rhabdomyoma			[16] [17] [18] [31] [32] [33]
Deep angiomyoxoma			[16] [17] [18]
Spindle cell nodule		Vaginal Solitary Fibrous Tumor	[9] [16] [17] [18] [34]
Undifferentiated carcinoma			[16] [17] [18]
Small cell carcinoma	no		[16] [17] [18]
Carcinoid	no		[18]
Adenoid basal carcinoma			[18]
Adenosquamous carcinoma	no		[18]
Adenoma	yes		[35]
Mucinous adenocarcinoma			[18]
Squamous papilloma	yes	vaginal micropapillomatosis	[16] [17] [18]
Endometrioid adenocarcinoma	no		[18]
Mesonephric adenocarcinoma			[18]
Clear cell adenocarcinoma	no		[16] [17] [18]
Fibroepithelial polyp	yes		[16] [17] [18]
Squamous intraepithelial neoplasia			[16] [17] [18]
Genital wart	yes	Condylomata acuminata	[6] [16] [17] [18]
Squamous cell carcinoma	no	Keratinizing, Nonkeratininzing, Basalaoid, Verrucous, Warty	[16] [17] [18]
Mesenchymal tumors			[18]
Alveolar soft part sarcoma			[18]
Mixed epithelial and mesenchymal Tumors			[18]
Malignant mixed Tumors resembling synovial sarcoma			[18]
Benign mixed tumors			[18]
Adenomatoid Tumor	yes		[18]
Malignant lymphoma	no		[18]
Granulocytic sarcoma			[18]
Fibroepithelial polyp	yes		[6] [17]
Verrucous carcinoma	no		[9]
Squamotransitional cell carcinoma			[9]

Other animals

Vaginal tumors also can be found in domesticated animals:

• Sarcoma botryoides
• Squamous cell carcinoma
• Condyloma acuminatum
• Squamous intraepithelial neoplasia
• Fibroepithelial polyp
• Clear-cell adenocarcinoma
• Squamous papilloma
• Leiomyoma
• Blue nevus
• Malignant melanoma
• Primitive neuroectodermal tumor
• Yolk sac tumor ^[36]

See also

• Urethral caruncle
• Vaginal cysts
• Vaginal intraepithelial neoplasia

Notes

References

External links

• Vagina, Anatomical Atlases, an Anatomical Digital Library (2018)