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I can attempt to add some information about this phenomenon, but it should probably be addressed by an MD or an MT/SBB (or equivalent). —Preceding unsigned comment added by 150.148.0.27 ( talk) 00:56, 8 December 2007 (UTC)
Indeed! This section needs to be re-worked. "The testing is difficult, since using different anti-D reagents, especially the older polyclonal reagents, may give different results." Most laboratories are using monoclonal murine reagents, and many have moved to "gel" technology which is much more specific. Give it a try! -- BloodGuru ( talk) 00:28, 23 May 2008 (UTC) MT (ASCP), MSIII
Should the rhesus factor page be merged with blood type? Snowman 17:26, 18 May 2006 (UTC)
I feel that the template should be changed - Rhesus system (or rhesus blood group system) featuring insead of rhesus factor. Snowman 12:13, 19 June 2006 (UTC)
Should one of the heading on this table be Rh status and not Rh (D) status? Snowman 08:45, 24 June 2006 (UTC)
The same table indicates Cde/Cde to be Rh positive, should it indicate Rh negative?G Snowman 13:51, 24 June 2006 (UTC)
I have done some work on the table layout, but I think that it aught to be possible to apply a style in a less verbose way to a whole column at a time. Snowman 14:15, 24 June 2006 (UTC)
"American Black"???, "Native American"??? This sounds like racism! Does anybody agrees with me? --
84.36.157.133 09:52, 6 September 2007 (UTC) Seriously? Would you also like us to remove "male" and "female" from the tables as it sounds like gender-bias?
Siege919 (
talk) 01:22, 13 February 2010 (UTC)
The whole ethnic labeling is very much geared towards an American audience. The use of the ethnic label "Caucasian" is rather confusing for non-American readers. Just say "European". Another thing, the high incidence of Rhesus negative among the Basque population ought to be further explained. Does it imply that the origin of the Rhesus negative gene should be sought in the southwest of Europe?? If so, wouldn't also a relative high percentage of North Africans have this gene as well?? —Preceding
unsigned comment added by
217.36.125.180 (
talk)
01:03, 28 November 2007 (UTC)
Just because a certain trait is common in a certain community (the Basque community in this case), does not imply that it originated over there. Rather, it's more likely because, it might have afforded a certain protective value to the ultimate phenotype (like how it is for sickle cell disease/trait and falciparum malaria.
In fact, talking of origins, it is explicitly mentioned in the article that the antigen was first found in macaques, so possibly, the gene traces its origin before the advent of humans. Ketan Panchal, MBBS ( talk) 07:01, 2 May 2008 (UTC)
It seems like the entry could be reorganized a bit for clarity, in particular the significance/preference of notation forms seemes to be featured too prominently. -- Belg4mit 00:06, 2 March 2007 (UTC)
Would appreciate it if there was a comment on how to test an individual's Rh factor. —The preceding unsigned comment was added by 158.228.241.114 ( talk) 18:34, 10 May 2007 (UTC).
Would be appreciated if someone would list the available transfusion matrix (i.e. O- is universal donor) —Preceding unsigned comment added by 76.16.138.78 ( talk) 07:45, 13 February 2008 (UTC)
Transfusing RH positive blood would cause trouble in an Rh negative patient by causing them to form an Anti D antibody. Once that is formed, only Rh negative blood can be safely transfused into the Rh negative patient. —Preceding unsigned comment added by Punkrokgrl78 ( talk • contribs) 01:11, 3 December 2009 (UTC)
Anybody know anything about R
Z, and how it relates to Rh? I know from a fictional reference and some real online article titles that it is rare and/or extinct and found in Native Americans, but that's it. —
MJBurrage(
T•
C)
03:12, 5 March 2008 (UTC)
I don't know why is there so much talk about merging the article, and organizational problem; I found the article quite alright, in fact, good. Any way, I would like to draw attention to the following paragraph:
"The Wiener system used the Rh-Hr nomenclature. This system theorized that there was one gene at a single locus on each chromosome of the pair which controls production of multiple antigens. This concept postulated that a gene R gives rise to the “blood factors” Rho, rh’, and hr” and the gene r will produce hr’ and hr”."
Are the "gene" in the above paragraph supposed to be "alleles", in which case, the whole thing would make better sense? I was, in fact, by myself going to change that to allele, but thought, it's better if I allow others to approve of my contention.
Ketan Panchal, MBBS ( talk) 07:22, 2 May 2008 (UTC)
Kindly see the table below:
Genotype | symbol | Rh(D) status |
---|---|---|
cde/cde | rr | Negative |
CDe/cde | R1r | Positive |
CDe/CDe | R1R1 | Positive |
cDE/cde | R2r | Positive |
CDe/cDE | R1R2 | Positive |
cDE/cDE | R2R2 | Positive |
Is it possible to have a genotype like Cde/Cde; cdE/cdE; or Cde/cdE? If yes, is there a particular reason, they don't find a mention in the table? I understand that, there phenotypes, if possibly expressed, will be Rh-negative. Is this so because, the expression of C and E genes is closely linked to the expression of the D gene? Are the alleles c and e, as against, C and E, recessive in any way?
43 other Rh group antigens have been described, but they are either much less frequently encountered or are rarely clinically significant. Each is given a number, though the highest assigned number (Rh56 or CENR) is not an accurate reflection of the antigens encountered since many (e.g. Rh38) have been combined, reassigned to other groups, or otherwise removed."--Are these other genes apart from the above mentioned RHD and RHCE genes, or different alleles of the same genes. If they are different genes on different loci, why are they known as the same Rh antigens, and not some other antigens?
Ketan Panchal, MBBS ( talk) 07:07, 2 May 2008 (UTC)
cDe | = | R0 |
CDe | = | R1 |
cDE | = | R2 |
CDE | = | RZ |
cde | = | r |
Cde | = | r′ |
cdE | = | r″ |
CdE | = | not listed |
cDe = R0 | CDe = R1 | cDE = R2 | CDE = RZ |
cde = r | Cde = r′ | cdE = r″ | CdE = rY |
Wow guys! Thanks so much for this entry. I finally understand!
In regards to Haemolytic Disease, if an Rh positive mother and an Rh positive father have two children, and the older child is Rh positive, does that mean that their younger child is Rh positive as well?-- Just James T/ C 06:59, 1 April 2009 (UTC)
This is a common misconception See for example Geoff Daniels at http://books.google.com/books?id=EIgT4d86l18C&lpg=PA33&ots=9GswZZQK_n&dq=rh%20not%20rhesus&pg=PA33 —Preceding unsigned comment added by 194.103.189.24 ( talk) 09:09, 2 July 2009 (UTC)
I can see the section 'Rhesus Factor' attempts to provide a simple explanation however it is still heavily laden with medical and bio science terms. Could someone add a less technical summary so that those reading the article without a degree in genetics or medicine can still gain a basic understanding the term. 83.104.138.141 ( talk) 04:37, 4 December 2009 (UTC)
Since the blood group system is called Rh and not Rhesus (it was a scientific error that lead to this wrong name in the first case), the present article should be renamed to Rh blood group system. Unfortunately, I do not know how to do this myself. The misnomer Rhesus blood group system should redirect to the new name. Thank you. -- Firefly's luciferase ( talk) 04:22, 6 December 2009 (UTC)
An editor has asked for a discussion to address the redirect Rh blood group system. Since you had some involvement with the Rh blood group system redirect, you might want to participate in the redirect discussion (if you have not already done so). Firefly's luciferase ( talk) 07:10, 6 December 2009 (UTC)
There is a lot of confusion on the terminology. Please consider in edits:
This section in the article just bases on the 2 references cited in the section above this one. Please add secondary sources to confirm this original research for the encyclopedia. Thanks. -- Firefly's luciferase ( talk) 05:31, 6 December 2009 (UTC)
As several people have mentioned above, the previous table listing phenotypes and genotypes was missing a lot of data. I've completed the list with every possible combination of haplotypes (excluding variants like CW etc.)
I noticed the table underneath it actually only references people in Turkey, so I've edited that in to make it clear how limited an area the data relates to.
Ideally I feel that the two tables should be combined, with a worldwide distribution rather than a single country. I know that there are differing racial distributions (for example the R0 haplotype is much more common in people of African origin than those of Caucasian origin) so it might be worth adding several columns to the end, one for each statistically relevant geographical variation. With that in place, I don't see a need to have a second table showing the differences between donated and required phenotypes in a single country. Magma ( talk) 11:21, 6 November 2010 (UTC)
Sections of this article are copied verbatim from http://americanpregnancy.org/pregnancy-complications/rh-factor/ — Preceding unsigned comment added by 108.7.200.30 ( talk) 03:26, 14 May 2016 (UTC)
The article fails to explain any connection between the c and C or e and E antigens. The table does not list any c−/C− phenotypes, but doesn't explain why they're not possible.
Here's what I think is going on:
If this is true, the article really needs to say so somewhere. 23.83.37.241 ( talk) 20:10, 22 January 2018 (UTC)
The article now reads, "It is the second most important blood group system, after the ABO blood group system." Important to what? I believe it means something like "important in medical practice" but thought I'd see what others think. IAmNitpicking ( talk) 13:29, 6 September 2019 (UTC)
I have to get a certain shot a couple months before delivery. 2601:5C1:300:D560:788B:7DF9:6312:7B2F ( talk) 21:40, 4 December 2021 (UTC)
Girl voice 2409:4043:197:4907:28B3:927F:96BD:B822 ( talk) 17:33, 11 February 2022 (UTC)
This article was the subject of a Wiki Education Foundation-supported course assignment, between 22 August 2022 and 9 December 2022. Further details are available
on the course page. Student editor(s):
Kedens2018 (
article contribs).
— Assignment last updated by Kedens2018 ( talk) 00:24, 2 September 2022 (UTC)
"According to a comprehensive study, the worldwide frequency of Rh-positive and Rh-negative blood types is approximately 00% and 00%, respectively." 2600:1700:9AA2:630:354C:35A7:38E8:F246 ( talk) 20:10, 5 March 2024 (UTC)