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Symbyax is a brand name used by Pfizer in marketing a combination of Fluoxetine and Olanzapine. There are a number of combination drug article in Wikipedia and if one is created for this combination, the redirect should be so retargeted. The current target is based on there being more treatment of Symbyax in the 'fluoxetine' article vs. the 'olanzapine' article. I'm not sure, but it is also likely that fluoxetine is considered the primary active in symbyax, with olanzapine added to alter the effects of fluoxetine (need pharmacologist input to verify that). --User:Ceyockey ( talk to me) 17:30, 18 December 2006 (UTC)
I welcome assistance. Persephone12 ( talk) 21:46, 17 July 2010 (UTC)
Some things I did to the article (and you might find interesting for your future article creations and expansions):
Things you could do to improve the article:
Hope this helps. Happy editing! ἀνυπόδητος ( talk) 22:32, 17 July 2010 (UTC)
Thanks a bunch for the help, I really had no idea how to deal with some of it, especially since it was a combination of drugs. Persephone12 ( talk) 22:46, 17 July 2010 (UTC)
I am not really sure, because I feel like adding much of the info typical to drug articles would essentially just be copying and pasting from olanzapine and fluoxetine. Thoughts? Persephone12 ( talk) 22:56, 17 July 2010 (UTC)
==Contraindications, adverse effects and interactions==
Contraindications, adverse effects and interactions are the same as for the constituent drugs.
Removed section on 'synergistic effects' of the combination of the two drugs, b/c the data given in the wiki entry does not appear in the associated citation. Moreover, claims along the lines of 'in a pre-clinical trial, xx% increase of [some neurotransmitter] was observed with drug X, yy% increase of [some neurotransmitter] was observed with drug y, and zz% increase of [some neurotransmitter] was observed when the two were used in combination' are woefully inadequate and misleading to appear in the wiki entry w/o further explication.
Very doubtful those numbers and claims pertain to in vivo measurements at the synaptic cleft in humans... although that is exactly what unsophisticated readers will assume. When the "catecholamine hypothesis" (or some variant thereof) is used in DTC advertising, it is highly misleading to make such statements without further additional information.
In future, please be much more forthright by providing both accurate citation and sufficient detail in the assertions themselves such that there is no ambiguity as to what experiments the measurements were derived from (in vivo/vitro, organism, method of sample collection and/or analyte detection, etc.) 71.202.140.109 ( talk) 10:55, 25 April 2012 (UTC)
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