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Hello all,
we are a group of clinical scientists and surgeons from the Charite University Hospital in Berlin, Germany. We have recently established a new enzymatic assaying method to measure extracellular nicotinamide adenine dinucleotide (eNAD) in human plasma. Given certain modifications, this assay could even be used to measure outher pyridine nucleotides in other body liquids.
We think that this assay can provide a valuable tool for clinical research into the regenerative potential of eNAD with respect to surgical inverventions (we are focusing on liver resection and transplantations) and healthy ageing.
Would it be adequate to add a paragraph or two under the Research section of this Wikipedia article?
Many thanks in advance for your opinions!
Pmbrrrrr ( talk) 18:36, 26 April 2020 (UTC)
/Fourier/Darwin/Einstein/Bohr/nucleic acids et al. continuum have conferred upon our times.—
JerzyA (
talk)
02:43, 24 June 2020 (UTC)
The sentence "Solutions of NAD+ are colorless and stable for about a week at 4 °C and neutral pH, but decompose rapidly in acids or alkalis. Upon decomposition, they form products that are enzyme inhibitors.[5]" is incorrect. The cited article refers to NADH solutions. According to Sigma Aldrich, NAD+ "Aqueous solutions between pH 2 - 6, stored as single-use aliquots at -70 °C, are stable for at least 6 months. Neutral or slightly acidic solutions are stable at 0 °C for at least 2 weeks." ( https://www.sigmaaldrich.com/content/dam/sigma-aldrich/docs/Sigma/Product_Information_Sheet/2/n8285pis.pdf) — Preceding unsigned comment added by 68.206.155.2 ( talk) 05:20, 6 October 2020 (UTC)