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This very good article needed some copyediting. I have lowercased all drug names that are not brand names, and similarly all diseases apart from the eponymous ones are lowercased on Wikipedia. I have also formatted the references, added PMIDs, and added categories. JFW | T@lk 4 July 2005 14:45 (UTC)
It was deliberate. There are very few articles with concluding remarks, and skimming over it I could not find anything that hadn't been covered in the article. But please leave it in if you prefer. JFW | T@lk 4 July 2005 16:37 (UTC)
What happened to the pictures of all the doctors involved? I thought they were very interesting. Matt 16:04, 5 April 2006 (UTC).
I am not happy with this page. The history of chemotherapy implies a little history of the therapy, and this reads more like a history of chemo. I would like to see some conclusions about the relative success of the original treatment regimens. Otherwise, what's there to show that any of it helped at all? Jane 13:17, 10 May 2006 (UTC).
This article mentions "the genetic nature of cancer" as a Scientific Truth, when there's evidence that seems to disprove that argument ( http://www.emediawire.com/releases/2006/4/prweb375398.php ). Please consider and make the following corrections, if warranted. Denvr 15:11, 5 June 2006 (UTC).
I'm new to wikipedia...
I knew most the principle actors mentioned in the article, made rounds with several (Farber, Holland, Davita.) Also worked at NCI under Zubrod... there's lots of details I could add to this...if its appropriate...
E.G.: Holland was the Chief of Medicine at Roswell Park in Buffalo in the mid Sioxties and chaired Acute Leukemia Group B, one of Zubrod's cooperative groups. He was frustrated by the brief duration of responses in breast cancer produced by the use of single agents (5FU,MTX, cyclophosphamide) give as weekly or monthly IV bolus. He was giving a talk at a community hospital outside Rochester, when a community physician approched to discuss a case and mentioned that he was giving all three drugs together and getting much better results. The combination was adopted as CMF and formed the basis for solid tumor chemotherapy.
(The reference is to Hollands first report of CMF in the Annals of Internal Medicine about 1970. The first or second author was the community physician) - User:CRoseMD1 05:20, 5 August 2006
Fixed a few minor grammatical things. This is a good article, but might benefit from a more "encyclopedic" tone. I did remove the statement that the lack of benefit from autologous transplant in breast cancer "dealt a severe blow to the medical oncology community". It was studied, it didn't work, and now it's not used anymore. That seems more encyclopedic. I also revised the final paragraph - death rates from the most common cancers have, in fact, dropped over the last 10 years (I added a citation to Abeloff's textbook to support this statement). Of course, a lot of this is due to prevention/screening rather than chemo, and I emphasized this in the revision. Thoughts? MastCell 17:58, 9 August 2006 (UTC)
This is still relevant and I will attempt to help. Knittea ( talk) 10:40, 17 July 2022 (UTC)
I believe Adriamycin was another important single agent therapy in the late 50s/early 60s - this should be added as it was a precursor to the CHOP and ABVD multiple chemotherapies used to successfully treat NHL/Hodgkin's respectfully. See http://www.lymphomainfo.net/therapy/drugs/adriamycin.html for some more info. -- 08:23, 14 November 2006 169.252.4.21 (talk)
The lack of dates and inline citations make it hard to understand what was actually happening. The whole article seems vaguely chronological but the section names make it look like work has been grouped by topic/approach. (Maybe based on a chapters from a book ?) More inline cites and dates would clarify. A particularly confusing section is "A period of quiet" completely without dates. - Rod57 ( talk) 23:31, 15 December 2012 (UTC)
At the beginning stands German Paul Ehrlich was earlier. He worked on that topic already in 1906. From Ehrlich also comes the word chemotherapy. 92.74.60.141 ( talk) 23:37, 15 May 2016 (UTC)