This article is within the scope of WikiProject Molecular Biology, a collaborative effort to improve the coverage of
Molecular Biology on Wikipedia. If you would like to participate, please visit the project page, where you can join
the discussion and see a list of open tasks.Molecular BiologyWikipedia:WikiProject Molecular BiologyTemplate:WikiProject Molecular BiologyMolecular Biology articles
This article is within the scope of WikiProject Cannabis, a collaborative effort to improve the coverage of
cannabis on Wikipedia. If you would like to participate, please visit the project page, where you can join
the discussion and see a list of open tasks.CannabisWikipedia:WikiProject CannabisTemplate:WikiProject CannabisCannabis articles
Before I began editing, these pages were a jumbled mess of confused science and faux-science that had clearly been compiled by recreational marijuana users with minimal understand of how solid research is conducted or reported. Most of the sections were written independently and did not read cohesively when considered by page; as such much of my efforts were spent cleaning up the inconsistencies, miscitations, and straight up fallacies that littered each topic discussed. In addition, I added more citations from appropriate and current research and reorganized the pages so that they are presented in a more digestable format.
In summary, these pages on endocannabinoid receptors were not lacking attention before my edits, but had rather received too much attention from people who just did not know what they were talking about. I have simplified, clarified, and expounded where appropriate with the intention of creating a more cohesive and through product. The extent of these edits are subtle, but were based on eight research pages that I read dealing with the topics I addressed — Preceding
unsigned comment added by
Wyliea (
talk •
contribs)
01:49, 7 December 2011 (UTC)reply
Image is misleading
The image ("Rendering based on PDB 2KI9") is not useful or representative in the context of an article about the full receptor. Removing the image would enhance this webpage. The image shows a single helix of a 7-helix bundle. I tried to edit the box, but everything looks auto-generated there, so I left it alone for a more experienced user to tackle.
External links modified
Hello fellow Wikipedians,
I have just modified one external link on
Cannabinoid receptor type 2. Please take a moment to review
my edit. If you have any questions, or need the bot to ignore the links, or the page altogether, please visit
this simple FaQ for additional information. I made the following changes:
When you have finished reviewing my changes, you may follow the instructions on the template below to fix any issues with the URLs.
This message was posted before February 2018.
After February 2018, "External links modified" talk page sections are no longer generated or monitored by InternetArchiveBot. No special action is required regarding these talk page notices, other than
regular verification using the archive tool instructions below. Editors
have permission to delete these "External links modified" talk page sections if they want to de-clutter talk pages, but see the
RfC before doing mass systematic removals. This message is updated dynamically through the template {{
source check}} (last update: 5 June 2024).
If you have discovered URLs which were erroneously considered dead by the bot, you can report them with
this tool.
If you found an error with any archives or the URLs themselves, you can fix them with
this tool.
Oddi S, Spagnuolo P, Bari M, D'Agostino A, Maccarrone M (2007). Differential modulation of type 1 and type 2 cannabinoid receptors along the neuroimmune axis. International Review of Neurobiology. Vol. 82. pp. 327–37.
doi:
10.1016/S0074-7742(07)82017-4.
ISBN978-0-12-373989-6.
PMID17678969.
Galiègue S, Mary S, Marchand J, Dussossoy D, Carrière D, Carayon P, Bouaboula M, Shire D, Le Fur G, Casellas P (Aug 1995). "Expression of central and peripheral cannabinoid receptors in human immune tissues and leukocyte subpopulations". European Journal of Biochemistry / FEBS. 232 (1): 54–61.
doi:
10.1111/j.1432-1033.1995.tb20780.x.
PMID7556170.
Munro S, Thomas KL, Abu-Shaar M (Sep 1993). "Molecular characterization of a peripheral receptor for cannabinoids". Nature. 365 (6441): 61–5.
doi:
10.1038/365061a0.
PMID7689702.
Shire D, Calandra B, Rinaldi-Carmona M, Oustric D, Pessègue B, Bonnin-Cabanne O, Le Fur G, Caput D, Ferrara P (Jun 1996). "Molecular cloning, expression and function of the murine CB2 peripheral cannabinoid receptor". Biochimica et Biophysica Acta. 1307 (2): 132–6.
doi:
10.1016/0167-4781(96)00047-4.
PMID8679694.
Tao Q, McAllister SD, Andreassi J, Nowell KW, Cabral GA, Hurst DP, Bachtel K, Ekman MC, Reggio PH, Abood ME (Mar 1999). "Role of a conserved lysine residue in the peripheral cannabinoid receptor (CB2): evidence for subtype specificity". Molecular Pharmacology. 55 (3): 605–13.
PMID10051546.
Nong L, Newton C, Friedman H, Klein TW (2002). "CB1 and CB2 receptor mRNA expression in human peripheral blood mononuclear cells (PBMC) from various donor types". In Friedman H, Klein TW, Madden JJ (eds.). Neuroimmune Circuits, Drugs of Abuse, and Infectious Diseases. Advances in Experimental Medicine and Biology. Vol. 493. pp. 229–33.
doi:
10.1007/0-306-47611-8_27.
ISBN978-0-306-46466-9.
PMID11727770.
Ho BY, Current L, Drewett JG (Jul 2002). "Role of intracellular loops of cannabinoid CB(1) receptor in functional interaction with G(alpha16)". FEBS Letters. 522 (1–3): 130–4.
doi:
10.1016/S0014-5793(02)02917-4.
PMID12095632.
Matias I, Pochard P, Orlando P, Salzet M, Pestel J, Di Marzo V (Aug 2002). "Presence and regulation of the endocannabinoid system in human dendritic cells". European Journal of Biochemistry / FEBS. 269 (15): 3771–8.
doi:
10.1046/j.1432-1033.2002.03078.x.
PMID12153574.
Song ZH, Feng W (Nov 2002). "Absence of a conserved proline and presence of a conserved tyrosine in the CB2 cannabinoid receptor are crucial for its function". FEBS Letters. 531 (2): 290–4.
doi:
10.1016/S0014-5793(02)03537-8.
PMID12417328.
Feng W, Song ZH (Apr 2003). "Effects of D3.49A, R3.50A, and A6.34E mutations on ligand binding and activation of the cannabinoid-2 (CB2) receptor". Biochemical Pharmacology. 65 (7): 1077–85.
doi:
10.1016/S0006-2952(03)00005-4.
PMID12663043.
Kishimoto S, Gokoh M, Oka S, Muramatsu M, Kajiwara T, Waku K, Sugiura T (Jul 2003). "2-arachidonoylglycerol induces the migration of HL-60 cells differentiated into macrophage-like cells and human peripheral blood monocytes through the cannabinoid CB2 receptor-dependent mechanism". The Journal of Biological Chemistry. 278 (27): 24469–75.
doi:
10.1074/jbc.M301359200.
PMID12711605.{{
cite journal}}: CS1 maint: unflagged free DOI (
link)
Jorda MA, Rayman N, Valk P, De Wee E, Delwel R (May 2003). "Identification, characterization, and function of a novel oncogene: the peripheral cannabinoid receptor Cb2". Annals of the New York Academy of Sciences. 996: 10–6.
doi:
10.1111/j.1749-6632.2003.tb03227.x.
PMID12799277.
Rayman N, Lam KH, Laman JD, Simons PJ, Löwenberg B, Sonneveld P, Delwel R (Feb 2004). "Distinct expression profiles of the peripheral cannabinoid receptor in lymphoid tissues depending on receptor activation status". Journal of Immunology. 172 (4): 2111–7.
doi:
10.4049/jimmunol.172.4.2111.
PMID14764676.
Rao GK, Zhang W, Kaminski NE (May 2004). "Cannabinoid receptor-mediated regulation of intracellular calcium by delta(9)-tetrahydrocannabinol in resting T cells". Journal of Leukocyte Biology. 75 (5): 884–92.
doi:
10.1189/jlb.1203638.
PMID14966196.
Alberich Jordà M, Rayman N, Tas M, Verbakel SE, Battista N, van Lom K, Löwenberg B, Maccarrone M, Delwel R (Jul 2004). "The peripheral cannabinoid receptor Cb2, frequently expressed on AML blasts, either induces a neutrophilic differentiation block or confers abnormal migration properties in a ligand-dependent manner". Blood. 104 (2): 526–34.
doi:
10.1182/blood-2003-12-4357.
PMID15039279.
Núñez E, Benito C, Pazos MR, Barbachano A, Fajardo O, González S, Tolón RM, Romero J (Sep 2004). "Cannabinoid CB2 receptors are expressed by perivascular microglial cells in the human brain: an immunohistochemical study". Synapse. 53 (4): 208–13.
doi:
10.1002/syn.20050.
PMID15266552.