From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Tumor protein p53-inducible nuclear protein 1 is a
protein that in humans is encoded by the TP53INP1
gene .
[5]
[6]
[7] In mice this protein is also called TRP53INP1 and is encoded by the Trp53inp1 gene. The protein is also referred to as SIP or "stress inducible protein"
Interactions
TP53INP1 has been shown to
interact with
HIPK2
[8] and
p53 .
[5]
[8]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000164938 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000028211 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
a
b Okamura S, Arakawa H, Tanaka T, Nakanishi H, Ng CC, Taya Y, Monden M, Nakamura Y (Aug 2001).
"p53DINP1, a p53-inducible gene, regulates p53-dependent apoptosis" . Mol Cell . 8 (1): 85–94.
doi :
10.1016/S1097-2765(01)00284-2 .
PMID
11511362 .
^ Nowak J, Tomasini R, Mattei MG, Azizi Samir LA, Dagorn JC, Dusetti N, Iovanna JL, Pebusque MJ (Nov 2002).
"Assignment of tumor protein p53 induced nuclear protein 1 (TP53INP1) gene to human chromosome band 8q22 by in situ hybridization" . Cytogenet Genome Res . 97 (1–2): 140E.
doi :
10.1159/000064049 .
PMID
12438758 .
^
"Entrez Gene: TP53INP1 tumor protein p53 inducible nuclear protein 1" .
^
a
b Tomasini, Richard; Samir Amina Azizi; Carrier Alice; Isnardon Daniel; Cecchinelli Barbara; Soddu Silvia; Malissen Bernard; Dagorn Jean-Charles; Iovanna Juan L; Dusetti Nelson J (Sep 2003).
"TP53INP1s and homeodomain-interacting protein kinase-2 (HIPK2) are partners in regulating p53 activity" . J. Biol. Chem . 278 (39). United States: 37722–9.
doi :
10.1074/jbc.M301979200 .
ISSN
0021-9258 .
PMID
12851404 .
Further reading
Tomasini R, Samir AA, Pebusque MJ, et al. (2003). "P53-dependent expression of the stress-induced protein (SIP)". Eur. J. Cell Biol . 81 (5): 294–301.
doi :
10.1078/0171-9335-00248 .
PMID
12067065 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Tomasini R, Samir AA, Carrier A, et al. (2003).
"TP53INP1s and homeodomain-interacting protein kinase-2 (HIPK2) are partners in regulating p53 activity" . J. Biol. Chem . 278 (39): 37722–9.
doi :
10.1074/jbc.M301979200 .
PMID
12851404 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5.
doi :
10.1038/ng1285 .
PMID
14702039 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Hershko T, Chaussepied M, Oren M, Ginsberg D (2005).
"Novel link between E2F and p53: proapoptotic cofactors of p53 are transcriptionally upregulated by E2F" . Cell Death Differ . 12 (4): 377–83.
doi :
10.1038/sj.cdd.4401575 .
PMID
15706352 .
Tomasini R, Seux M, Nowak J, et al. (2006).
"TP53INP1 is a novel p73 target gene that induces cell cycle arrest and cell death by modulating p73 transcriptional activity" . Oncogene . 24 (55): 8093–104.
doi :
10.1038/sj.onc.1208951 .
PMID
16044147 .
Jiang PH, Motoo Y, Garcia S, et al. (2006).
"Down-expression of tumor protein p53-induced nuclear protein 1 in human gastric cancer" . World J. Gastroenterol . 12 (5): 691–6.
doi :
10.3748/wjg.v12.i5.691 .
PMC
4066117 .
PMID
16521180 .
Ito Y, Motoo Y, Yoshida H, et al. (2007). "High level of tumour protein p53-induced nuclear protein 1 (TP53INP1) expression in anaplastic carcinoma of the thyroid". Pathology . 38 (6): 545–7.
doi :
10.1080/00313020601024094 .
PMID
17393983 .
S2CID
28578199 .
Bernardo MV, Yelo E, Gimeno L, et al. (2007). "Identification of apoptosis-related PLZF target genes". Biochem. Biophys. Res. Commun . 359 (2): 317–22.
doi :
10.1016/j.bbrc.2007.05.085 .
PMID
17537403 .