From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
TIMELESS-interacting protein is a
protein that in humans is encoded by the TIPIN
gene .
[5]
[6]
[7]
Interactions
TIPIN has been shown to
interact with
Replication protein A1 .
[8]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000075131 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000032397 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Gotter AL (Aug 2003). "Tipin, a novel timeless-interacting protein, is developmentally co-expressed with timeless and disrupts its self-association". Journal of Molecular Biology . 331 (1): 167–76.
doi :
10.1016/S0022-2836(03)00633-8 .
PMID
12875843 .
^ Yoshizawa-Sugata N, Masai H (Jan 2007).
"Human Tim/Timeless-interacting protein, Tipin, is required for efficient progression of S phase and DNA replication checkpoint" . The Journal of Biological Chemistry . 282 (4): 2729–40.
doi :
10.1074/jbc.M605596200 .
PMID
17102137 .
^
"Entrez Gene: TIPIN TIMELESS interacting protein" .
^ Unsal-Kaçmaz K, Chastain PD, Qu PP, Minoo P, Cordeiro-Stone M, Sancar A, Kaufmann WK (Apr 2007).
"The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement" . Molecular and Cellular Biology . 27 (8): 3131–42.
doi :
10.1128/MCB.02190-06 .
PMC
1899931 .
PMID
17296725 .
Further reading
Unsal-Kaçmaz K, Chastain PD, Qu PP, Minoo P, Cordeiro-Stone M, Sancar A, Kaufmann WK (Apr 2007).
"The human Tim/Tipin complex coordinates an Intra-S checkpoint response to UV that slows replication fork displacement" . Molecular and Cellular Biology . 27 (8): 3131–42.
doi :
10.1128/MCB.02190-06 .
PMC
1899931 .
PMID
17296725 .
Gotter AL, Suppa C, Emanuel BS (Feb 2007).
"Mammalian TIMELESS and Tipin are evolutionarily conserved replication fork-associated factors" . Journal of Molecular Biology . 366 (1): 36–52.
doi :
10.1016/j.jmb.2006.10.097 .
PMC
4151250 .
PMID
17141802 .
Chou DM, Elledge SJ (Nov 2006).
"Tipin and Timeless form a mutually protective complex required for genotoxic stress resistance and checkpoint function" . Proceedings of the National Academy of Sciences of the United States of America . 103 (48): 18143–7.
Bibcode :
2006PNAS..10318143C .
doi :
10.1073/pnas.0609251103 .
PMC
1654129 .
PMID
17116885 .
Simpson JC, Wellenreuther R, Poustka A, Pepperkok R, Wiemann S (Sep 2000).
"Systematic subcellular localization of novel proteins identified by large-scale cDNA sequencing" . EMBO Reports . 1 (3): 287–92.
doi :
10.1093/embo-reports/kvd058 .
PMC
1083732 .
PMID
11256614 .
Bonaldo MF, Lennon G, Soares MB (Sep 1996).
"Normalization and subtraction: two approaches to facilitate gene discovery" . Genome Research . 6 (9): 791–806.
doi :
10.1101/gr.6.9.791 .
PMID
8889548 .