Sylvie Garneau-Tsodikova is a French Canadian-American chemist who is a Professor and Associate Vice President for Research at the University of Kentucky. One of the areas of her research interest is the development of new molecules to combat bacterial and fungal resistance.

Garneau-Tsodikova was born in Quebec City, Canada. She attended the Université Laval for her undergraduate studies in chemistry, where she graduated top of the class. ^[1] As a student, she was honoured with several awards, including distinguishments from the Chemical Institute of Canada and Natural Sciences and Engineering Research Council. ^[1] She completed a Master's thesis on the synthesis of glutamyl transfer RNA synthetase inhibitors. ^[2] She moved to the University of Alberta for graduate studies, where she worked on the impact of antimicrobial agents of bacterial cell walls. ^{[3] [4]} During her doctoral studies she became interested in infectious diseases and the development of antibacterial agents. ^[5]

Garneau-Tsodikova moved to the Harvard Medical School for her postdoctoral training where she worked with Christopher T. Walsh on the formation and modification of di pyrroles. At Harvard she was trained in both enzymology and biochemistry. In 2006, Garneau-Tsodikova moved to the University of Michigan, where she was an Assistant Professor of Medicinal Chemistry. ^[6] She spent seven years at Michigan, until she moved to the University of Kentucky. She was promoted to Professor and Assistant Dean in 2018. ^[7]

Garneau-Tsodikova's research focuses on the development of antifungal and antibacterial agents. ^[5] In particular, Garneau-Tsodikova focused on drug resistance in tuberculosis and in fungal infections by Candida auris. ^[5] She was also involved in the development of multifunctional enzymes with tunable biological properties. She served as an Associate Editor of the Royal Society of Chemistry journal MedChemComm, now called RSC Medicinal Chemistry. ^[8]

• Christopher T Walsh; Sylvie Garneau-Tsodikova; Gregory J Gatto (1 December 2005). "Protein posttranslational modifications: the chemistry of proteome diversifications". Angewandte Chemie International Edition. 44 (45): 7342–7372. doi: 10.1002/ANIE.200501023. ISSN  1433-7851. PMID  16267872. Wikidata  Q34465021.
• Frédéric H Vaillancourt; Ellen Yeh; David A Vosburg; Sylvie Garneau-Tsodikova; Christopher T Walsh (1 August 2006). "Nature's inventory of halogenation catalysts: oxidative strategies predominate". Chemical Reviews. 106 (8): 3364–3378. doi: 10.1021/CR050313I. ISSN  0009-2665. PMID  16895332. Wikidata  Q34555225.
• Sylvie Garneau; Nathaniel I Martin; John C Vederas (1 May 2002). "Two-peptide bacteriocins produced by lactic acid bacteria". Biochimie. 84 (5–6): 577–592. doi: 10.1016/S0300-9084(02)01414-1. ISSN  0300-9084. PMID  12423802. Wikidata  Q34992720.