Shain may refer to:

• Shain, alternate name of Hashatjin, a city in Ardabil Province, Iran

• Charles Alexander Shain (1922–1960), Australian astronomer
• Eva Shain (1918–1999), American boxing judge
• Irving Shain (1926–2018), American academic
• Jon Shain (born 1967), American folk musician
• Merle Shain (1935–1989), Canadian author and journalist
• Milton Shain, (born 1949), South African historian
• Ruchoma Shain (1914–2013), American teacher and author
• Yossi Shain (born 1956), Israeli academic and politician

• Shaina
• Shein (disambiguation)

This disambiguation page lists articles associated with the title Shain.
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