Sesquiterpene lactones (SLs) are a class of
sesquiterpenoids that contain a
lactone ring. They are most often found in plants of the family
Asteraceae (daisies, asters). Other plant families with SLs are
Umbelliferae (celery, parsley, carrots) and
Magnoliaceae (magnolias). A collection of colorless, lipophilic solids, SLs are a rich source of drugs.[1] They can be allergenic and toxic in grazing livestock[2] causing severe
neurological problems in horses. Some are also found in corals of the order Alcyonacea.
One eudesmanolide, 3-oxo-5αH,8βH-eudesma-1,4(15),7(11)-trien-8,12-olide, can work with
vernolic acid and other compounds in plants to reduce inflammation.[3]
^Amaya S, Pereira JA, Borkosky SA, Valdez JC, Bardón A, Arena ME (October 2012). "Inhibition of quorum sensing in Pseudomonas aeruginosa by sesquiterpene lactones". Phytomedicine. 19 (13): 1173–7.
doi:
10.1016/j.phymed.2012.07.003.
hdl:11336/77653.
PMID22925726.