Clinical data | |
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Trade names | Simparica |
Other names | PF-6450567 |
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ECHA InfoCard | 100.234.000 |
Chemical and physical data | |
Formula | C23H18Cl2F4N2O5S |
Molar mass | 581.36 g·mol−1 |
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Sarolaner, sold under the brand name Simparica, is an ectoparasiticide veterinary medication for the treatment of flea and tick infestations in dogs. [3] [4] It is also used off-label to control sarcoptic mange and demodectic mange. [4]
Sarolaner is also a component of the combination drug Simparica Trio, which contains sarolaner, moxidectin, and pyrantel. [5] It is used for prevention of heartworm disease caused by Dirofilaria immitis; treat and prevent flea infestations; treat and control tick infestations with the lone star tick, Gulf Coast tick, American dog tick, black-legged tick, and brown dog tick; and treat and control roundworm and adult hookworm infections. [6]
Sarolaner is also an ingredient in feline combination antiparasitic Revolution Plus (or Stronghold Plus [7]), which contains sarolaner and selamectin and is used for prevention of sarcoptic mange, feline hookworms, feline roundworms, ear mites, and heartworms, as well as treating and preventing fleas and ticks. [8]