Translocon-associated protein subunit beta also known as TRAP-beta is a
protein that in humans is encoded by the SSR2gene.[5][6]
Function
The signal sequence receptor (SSR) is a
glycosylatedendoplasmic reticulum (ER) membrane receptor associated with
protein translocation across the ER membrane. The SSR consists of 2 subunits, a 34-kD glycoprotein (alpha-SSR or
SSR1) and a 22-kD glycoprotein (beta-SSR or SSR2). The human beta-signal sequence receptor gene (SSR2) maps to chromosome bands 1q21-q23.[6]
^"Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^"Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^Chinen K, Sudo K, Takahashi E, Nakamura Y (Jul 1995). "Isolation and mapping of the human beta-signal sequence receptor gene (SSR2)". Cytogenetics and Cell Genetics. 70 (3–4): 215–7.
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10.1159/000134036.
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10.1016/0378-1119(94)90802-8.
PMID8125298.
Bodescot M, Brison O (January 1994). "Cloning and sequence analysis of the beta subunit of the human translocon-associated protein". Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression. 1217 (1): 101–2.
doi:
10.1016/0167-4781(94)90131-7.
PMID8286409.
Suzuki Y, Yoshitomo-Nakagawa K, Maruyama K, Suyama A, Sugano S (October 1997). "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library". Gene. 200 (1–2): 149–56.
doi:
10.1016/S0378-1119(97)00411-3.
PMID9373149.
Zhang H, Li XJ, Martin DB, Aebersold R (June 2003). "Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry". Nature Biotechnology. 21 (6): 660–6.
doi:
10.1038/nbt827.
PMID12754519.
S2CID581283.