From Wikipedia, the free encyclopedia
Rosiridin
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Names
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IUPAC name
(2R,3R,4S,5S,6R)-2-{[(2E,4S)-4-Hydroxy-3,7-dimethylocta-2,6-dien-1-yl]oxy}-6-(hydroxymethyl)oxane-3,4,5-triol
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Identifiers
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UNII
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CC(=CC[C@@H](/C(=C/CO[C@H]1[C@@H]([C@H]([C@@H]([C@H](O1)CO)O)O)O)/C)O)C
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Properties
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C16H28O7
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Molar mass
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332.393 g·mol−1
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Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Rosiridin is a
chemical compound that has been isolated from
Rhodiola sachalinensis.
[1] Rosiridin can inhibit
monoamine oxidases A and B, possibly meaning that the compound could help in the treatment of
depression and
senile dementia.
[2]
[3]
References
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^ Yoshikawa, Masayuki; Nakamura, Seikou; Li, Xuezheng; Matsuda, Hisashi (2008).
"Reinvestigation of absolute stereostructure of (−)-rosiridol: Structures of monoterpene glycosides, rosiridin, rosiridosides A, B, and C, from Rhodiola sachalinesnsis". Chemical and Pharmaceutical Bulletin. 56 (5): 695–700.
doi:
10.1248/cpb.56.695.
PMID
18451561.
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^ Panossian, Alexander; Wikman, Georg (2010).
"Effects of adaptogens on the central nervous system and the molecular mechanisms associated with their stress-protective activity". Pharmaceuticals. 3 (1): 188–224.
doi:
10.3390/ph3010188.
PMC
3991026.
PMID
27713248.
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^ van Diermen, Daphne; Marston, Andrew; Bravo, Juan; Reist, Marianne; Carrupt, Pierre-Alain; Hostettmann, Kurt (2009-03-18).
"Monoamine oxidase inhibition by Rhodiola rosea L. roots". Journal of Ethnopharmacology. 122 (2): 397–401.
doi:
10.1016/j.jep.2009.01.007.
ISSN
0378-8741.