Hossain was a professor of the civil engineering department of Khulna University of Engineering & Technology.[4]
On 13 August 2018, Hossain was appointed the vice-chancellor of the Khulna University of Engineering & Technology.[3][5] He received three new buses for the university in 2019.[6]
Hossain closed the Khulna University of Engineering & Technology in the first week of December 2021 after students and teachers were agitated over the death of professor Mohammad Selim Hossain who died following harassment by
Bangladesh Chhatra League activists.[7][8]
In August 2022, Hossain signed an agreement with
Huawei to establish an ICT academy at the Khulna University of Engineering & Technology.[9][10]