Prodilidine is an
opioidanalgesic which is a ring-contracted analogue of
prodine. It has around the same analgesic efficacy as
codeine, but is only around 1/3 the potency (100mg prodilidine is equivalent to 3mg oral morphine). It has little
abuse potential.[1][2][3][4][5]
^Splitter SR (November 1961). "Treatment of pain in patients with a new nonnarcotic analgesic, prodilidine hydrochloride (Cogesic)". Current Therapeutic Research, Clinical and Experimental. 3: 472–7.
PMID13915874.
^Kissel JW, Albert JR, Boxill GC (December 1961). "The pharmacology of prodilidine hydrochloride, a new analgetic agent". The Journal of Pharmacology and Experimental Therapeutics. 134: 332–40.
PMID14456453.
^Weikel JH, Labudde JA (December 1962). "Absorption, excretion and fate of prodilidine". The Journal of Pharmacology and Experimental Therapeutics. 138: 392–8.
PMID13999550.
^Batterman RC, Mouratoff GJ, Kaufman JE (January 1964). "Prodilidine Hydrochloride: A new moderately potent analgesic". The American Journal of the Medical Sciences. 247: 62–8.
doi:
10.1097/00000441-196401000-00009.
PMID14106881.
S2CID41209143.