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Did you know
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Portal:Medicine/Did you know/9
- ...the
brain itself is not sensitive to
pain, because it lacks pain-sensitive nerve fibers? Several areas of the head can
hurt, including a network of nerves which extends over the scalp and certain nerves in the face, mouth, and throat.
- ...that
irritable bowel syndrome (IBS) may sometimes have an acute onset and develop after an
infectious illness, and that this "Post infectious IBS" (IBS-PI) is drawing much clinical investigation?
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- ...that during the "Age of
Heroic Medicine" (1780-1850), educated professional physicians aggressively practiced "heroic medicine", including
bloodletting (venesection), intestinal purging (
calomel), vomiting (tartar
emetic), profuse sweating (
diaphoretics) and
blistering? These medical treatments were well-intentioned, and often well-accepted by the medical community, but were actually harmful to the patient.
- ...
thalidomide is a drug that was sold during the late
1950s and
1960s to pregnant women as an
antiemetic? It was later found to be
teratogenic, causing
amelia and
phocomelia. However, it is still used for other indications such as for
leprosy and
multiple myeloma, with close regulation through the System for Thalidomide Education and Prescribing Safety (STEPS) program.
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- ...
Genotoxicity is the proper term for the DNA damaging property of many
carcinogens. These chemicals alter DNA to induce mutations and then
apoptosis. While this is a common property in chemicals that cause cancer it is also a property in drugs that fight cancer; these drugs alter the DNA of cancerous cells leading to mutations in cancer cells and eventual cell death.
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- ...the symptoms of
Alzheimer's disease as a distinct entity were first identified by
Emil Kraepelin, and the characteristic neuropathology was first observed by
Alois Alzheimer, a German psychiatrist, in
1906? In this sense, the disease was co-discovered by Kraepelin and Alzheimer, who worked in Kraepelin's laboratory. Because of the overwhelming importance Kraepelin attached to finding the neuropathological basis of psychiatric disorders, Kraepelin made the generous decision that the disease would bear Alzheimer's name.
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