Kenneth Plume (born 1977), American author and broadcaster
Mike Plume (born 1968), Canadian country music singer and songwriter
Roberts Plūme (1897–1956), Latvian cyclist and cross-country skier
Thomas Plume (1630–1704), English churchman and philanthropist, founder of the Plume School
Software
Plume, an activitypub powered federated blogging application
PLUME, a free and open-source software toolbox that allows for the exhaustive recording of Unity applications with a focus on XR behavioral data (including synchronous physiological signals), their offline interactive replay and analysis.
Other uses
Plume (company), a company that provides smart WiFi services for personal households
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