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Per Uhlén
Born1969 (age 54–55)
Uppsala, Sweden
EducationKarolinska Institutet (PhD), Kungliga Tekniska Högskolan (MSc), Yale University (Postdoc), Marine Biology Laboratory (Postdoc)
OccupationProfessor
Employer Karolinska Institute
Website www.uhlenlab.org

Per Uhlén, born in 1969 in Uppsala, is a Swedish researcher in cell and molecular biology and professor of cell signaling at Karolinska Institute in Stockholm. Uhlén conducts research about cell signaling and how different cues affect important biological processes for cancer and development, such as cell division, cell differentiation and cell death. [1] [2] [3] Uhlén is also conducting research using three-dimensional (3D) imaging with light sheet fluorescence microscopy and tissue clearing to map, characterize, and diagnose intact tumor samples. [4] [5]

Uhlén began studying engineering physics at the Royal Institute of Technology (KTH) in Stockholm in 1993 and graduated with a master's degree in engineering in 1998. He then began doctoral studies at Karolinska Institute and became a doctor of philosophy (PhD) in 2002 with the thesis "Signal Transduction Via Ion Fluxes". After his dissertation, Uhlén moved to the United States to conduct postdoctoral research in Barbara Ehrlich's laboratory at Yale University in New Haven, CT. During his postdoc stay in the United States, Uhlén also conducted research at the Marine Biology Laboratory (MBL) in Woods Hole, MA. In 2006, Uhlén returned to Sweden to establish his own research group at Karolinska Institute. Uhlén became an associate professor (Docent) in 2009 and a full professor in 2014.

Uhlén has participated in two Paralympic Games in Atlanta (1996) and Sydney (2020), where he played wheelchair basketball in Sweden at the 2000 Summer Paralympics and also played in a rock band with Atomic Swing's frontman Niclas Frisk.

References

  1. ^ Uhlén P, Laestadius A, Jahnukainen T, Söderblom T, Bäckhed F, Celsi G; et al. (2000). "Alpha-haemolysin of uropathogenic E. coli induces Ca2+ oscillations in renal epithelial cells". Nature. 405 (6787): 694–7. Bibcode: 2000Natur.405..694U. doi: 10.1038/35015091. PMID  10864327. S2CID  4420606.{{ cite journal}}: CS1 maint: multiple names: authors list ( link)
  2. ^ Uhlén P (2004). "Spectral analysis of calcium oscillations". Sci STKE. 2004 (258): pl15. doi: 10.1126/stke.2582004pl15. PMID  15536176. S2CID  35396419.
  3. ^ Malmersjö S, Rebellato P, Smedler E, Planert H, Kanatani S, Liste I; et al. (2013). "Neural progenitors organize in small-world networks to promote cell proliferation". Proc Natl Acad Sci U S A. 110 (16): E1524-32. Bibcode: 2013PNAS..110E1524M. doi: 10.1073/pnas.1220179110. PMC  3631687. PMID  23576737.{{ cite journal}}: CS1 maint: multiple names: authors list ( link)
  4. ^ Tanaka N, Kanatani S, Tomer R, Sahlgren C, Kronqvist P, Kaczynska D; et al. (2017). "Whole-tissue biopsy phenotyping of three-dimensional tumours reveals patterns of cancer heterogeneity". Nat Biomed Eng. 1 (10): 796–806. doi: 10.1038/s41551-017-0139-0. PMID  31015588. S2CID  256713371.{{ cite journal}}: CS1 maint: multiple names: authors list ( link)
  5. ^ Tanaka N, Kanatani S, Kaczynska D, Fukumoto K, Louhivuori L, Mizutani T; et al. (2020). "Three-dimensional single-cell imaging for the analysis of RNA and protein expression in intact tumour biopsies". Nat Biomed Eng. 4 (9): 875–888. doi: 10.1038/s41551-020-0576-z. PMID  32601394. S2CID  256704785.{{ cite journal}}: CS1 maint: multiple names: authors list ( link)

External links