From Wikipedia, the free encyclopedia
Papuamides A and B are
depsipeptides which appear to protect
T cells from
HIV.
[1] They were isolated from the
sponge
Theonella,
[1] and are part of a larger group of structurally similar depsipeptides—also isolated from sponges—including
neamphamide A,
callipeltin A, and
mirabamides A-D.
[2]
References
- ^
a
b Ford, PW; Gustafson, KR; McKee, TC; Shigematsu, N; Maurizi, LK; Pannell, LK; Williams, DE; de Silva, ED; Lassota, P; Allen, TM; Van Soest, R; Andersen, RJ; Boyd, MR (1999). "Papuamides A-D, HIV-Inhibitory and Cytotoxic Depsipeptides from the Sponges Theonella mirabilis and Theonella swinhoei Collected in Papua New Guinea. J. Am. Chem. Soc". 121: 5899–5909.
-
^ Andjelic, CD; Planelles, V; Barrows, LR (2008).
"Characterizing the Anti-HIV Activity of Papuamide A. Mar Drugs". Marine Drugs. 6 (4): 528–49.
doi:
10.3390/md20080027.
PMC
2630844.
PMID
19172193.