From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Pygopus homolog 2 is a
protein that in humans is encoded by the PYGO2
gene .
[5]
[6]
References
Further reading
Kramps T, Peter O, Brunner E, et al. (2002).
"Wnt/wingless signaling requires BCL9/legless-mediated recruitment of pygopus to the nuclear beta-catenin-TCF complex" (PDF) . Cell . 109 (1): 47–60.
doi :
10.1016/S0092-8674(02)00679-7 .
PMID
11955446 .
S2CID
16720801 . Archived from
the original (PDF) on 2021-09-26. Retrieved 2021-01-31 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Townsley FM, Thompson B, Bienz M (2004).
"Pygopus residues required for its binding to Legless are critical for transcription and development" . J. Biol. Chem . 279 (7): 5177–83.
doi :
10.1074/jbc.M309722200 .
PMID
14612447 .
S2CID
6880212 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5.
doi :
10.1038/ng1285 .
PMID
14702039 .
S2CID
21903526 .
Brandenberger R, Wei H, Zhang S, et al. (2005). "Transcriptome characterization elucidates signaling networks that control human ES cell growth and differentiation". Nat. Biotechnol . 22 (6): 707–16.
doi :
10.1038/nbt971 .
PMID
15146197 .
S2CID
27764390 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The Status, Quality, and Expansion of the NIH Full-Length cDNA Project: The Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Wan D, Gong Y, Qin W, et al. (2004).
"Large-scale cDNA transfection screening for genes related to cancer development and progression" . Proc. Natl. Acad. Sci. U.S.A . 101 (44): 15724–9.
Bibcode :
2004PNAS..10115724W .
doi :
10.1073/pnas.0404089101 .
PMC
524842 .
PMID
15498874 .
Popadiuk CM, Xiong J, Wells MG, et al. (2006).
"Antisense suppression of pygopus2 results in growth arrest of epithelial ovarian cancer" . Clin. Cancer Res . 12 (7 Pt 1): 2216–23.
doi :
10.1158/1078-0432.CCR-05-2433 .
PMID
16609037 .
S2CID
3260972 .
Beausoleil SA, Villén J, Gerber SA, et al. (2006). "A probability-based approach for high-throughput protein phosphorylation analysis and site localization". Nat. Biotechnol . 24 (10): 1285–92.
doi :
10.1038/nbt1240 .
PMID
16964243 .
S2CID
14294292 .
Hoffmans R, Basler K (2007).
"BCL9-2 binds Arm/beta-catenin in a Tyr142-independent manner and requires Pygopus for its function in Wg/Wnt signaling" . Mech. Dev . 124 (1): 59–67.
doi :
10.1016/j.mod.2006.09.006 .
PMID
17113272 .
S2CID
17642255 .
Andrews PG, Lake BB, Popadiuk C, Kao KR (2007). "Requirement of Pygopus 2 in breast cancer". Int. J. Oncol . 30 (2): 357–63.
doi :
10.3892/ijo.30.2.357 (inactive 31 January 2024).
PMID
17203217 . {{
cite journal }}
: CS1 maint: DOI inactive as of January 2024 (
link )