Names | |
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IUPAC name
6-{2-[(2E)-2-Buten-2-yl]-8-[4-(dimethylamino)-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl]-11-hydroxy-5-methyl-4,7,12-trioxo-7,12-dihydro-4H-naphtho[2,3-h]chromen-10-yl}-4-(dimethylamino)-2,4-dimethyltetrahydro-2H-pyran-3-yl acetate
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Identifiers | |
3D model (
JSmol)
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ChEMBL | |
ChemSpider | |
PubChem
CID
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Properties | |
C41H50N2O10 | |
Molar mass | 730.855 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Neopluramycin is an antibiotic that inhibits
nucleic acid synthesis. It has been isolated from the cultured broth of a strain of
Streptomyces pluricolorescens as orange crystals, and analytical data and molecular weight determination are consistent with the empirical formula C
41H
50N
2O
10.
[1]
Neopluramycin resembles pluramycin A, but is differentiated by its antibacterial spectrum, toxicity, thin-layer chromatography, and infrared absorption spectrum. [1]
Neopluramycin inhibits growth of Gram-positive bacteria, leukemia L-1210 in mice and Yoshida rat sarcoma cells in tissue culture. [1] [2]