Names | |
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Preferred IUPAC name
tert-Butyl {2-[(2-aminoethyl)disulfanyl]ethyl}carbamate | |
Identifiers | |
3D model (
JSmol)
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ChemSpider | |
PubChem
CID
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UNII | |
CompTox Dashboard (
EPA)
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Properties | |
C9H20N2O2S2 | |
Molar mass | 252.39 g·mol−1 |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Mono-BOC-cystamine (mono BOC protected cystamine) is a tert-butyloxycarbonyl (BOC) derivative of cystamine used as crosslinker in biotechnology and molecular biology applications. [1] This compound was originally reported by Hansen et al. [2]
The disulfide chain allows the mono-BOC-cystamine to be easily cleaved, allowing removal of the tagging residue when desired.
Mono-BOC-cystamine is used as a crosslinker for the synthesis of cleavable photo-cross-linking reagent. [3]
Mono-BOC-cystamine is used as a crosslinker for the synthesis of a biodegradable cystamine spacer in PGA-cystamine-Gd-DO3A, which shows improved MRI contrast for breast carcinoma imaging in mice. [4]