From Wikipedia, the free encyclopedia
Non-coding RNA in the species Homo sapiens
MicroRNA 425 is a
microRNA that in humans is encoded by the MIR425
gene .
[1]
References
Further reading
Liang D, Meyer L, Chang DW, Lin J, Pu X, Ye Y, Gu J, Wu X, Lu K (December 2010).
"Genetic variants in MicroRNA biosynthesis pathways and binding sites modify ovarian cancer risk, survival, and treatment response" . Cancer Res . 70 (23): 9765–76.
doi :
10.1158/0008-5472.CAN-10-0130 .
PMC
5373101 .
PMID
21118967 .
Di Leva G, Piovan C, Gasparini P, Ngankeu A, Taccioli C, Briskin D, Cheung DG, Bolon B, Anderlucci L, Alder H, Nuovo G, Li M, Iorio MV, Galasso M, Santhanam R, Ramasamy S, Marcucci G, Perrotti D, Powell KA, Bratasz A, Garofalo M, Nephew KP, Croce CM (2013).
"Estrogen mediated-activation of miR-191/425 cluster modulates tumorigenicity of breast cancer cells depending on estrogen receptor status" . PLOS Genet . 9 (3): e1003311.
doi :
10.1371/journal.pgen.1003311 .
PMC
3591271 .
PMID
23505378 .
Arora P, Wu C, Khan AM, Bloch DB, Davis-Dusenbery BN, Ghorbani A, Spagnolli E, Martinez A, Ryan A, Tainsh LT, Kim S, Rong J, Huan T, Freedman JE, Levy D, Miller KK, Hata A, Del Monte F, Vandenwijngaert S, Swinnen M, Janssens S, Holmes TM, Buys ES, Bloch KD, Newton-Cheh C, Wang TJ (August 2013).
"Atrial natriuretic peptide is negatively regulated by microRNA-425" . J. Clin. Invest . 123 (8): 3378–82.
doi :
10.1172/JCI67383 .
PMC
3726159 .
PMID
23867623 .
Ma J, Liu J, Wang Z, Gu X, Fan Y, Zhang W, Xu L, Zhang J, Cai D (February 2014).
"NF-kappaB-dependent microRNA-425 upregulation promotes gastric cancer cell growth by targeting PTEN upon IL-1β induction" . Mol. Cancer . 13 : 40.
doi :
10.1186/1476-4598-13-40 .
PMC
3941686 .
PMID
24571667 .
Peng WZ, Ma R, Wang F, Yu J, Liu ZB (March 2014).
"Role of miR-191/425 cluster in tumorigenesis and diagnosis of gastric cancer" . Int J Mol Sci . 15 (3): 4031–48.
doi :
10.3390/ijms15034031 .
PMC
3975382 .
PMID
24603541 .
Moskwa P, Zinn PO, Choi YE, Shukla SA, Fendler W, Chen CC, Lu J, Golub TR, Hjelmeland A, Chowdhury D (December 2014).
"A functional screen identifies miRs that induce radioresistance in glioblastomas" . Mol. Cancer Res . 12 (12): 1767–78.
doi :
10.1158/1541-7786.MCR-14-0268 .
PMC
4386891 .
PMID
25256711 .
Liu P, Hu Y, Ma L, Du M, Xia L, Hu Z (October 2015). "miR-425 inhibits melanoma metastasis through repression of PI3K-Akt pathway by targeting IGF-1". Biomed. Pharmacother . 75 : 51–7.
doi :
10.1016/j.biopha.2015.08.010 .
PMID
26463631 .
Zhang Y, Hu X, Miao X, Zhu K, Cui S, Meng Q, Sun J, Wang T (February 2016).
"MicroRNA-425-5p regulates chemoresistance in colorectal cancer cells via regulation of Programmed Cell Death 10" . J. Cell. Mol. Med . 20 (2): 360–9.
doi :
10.1111/jcmm.12742 .
PMC
4727563 .
PMID
26647742 .
Liu L, Zhao Z, Zhou W, Fan X, Zhan Q, Song Y (November 2015). "Enhanced Expression of miR-425 Promotes Esophageal Squamous Cell Carcinoma Tumorigenesis by Targeting SMAD2". J Genet Genomics . 42 (11): 601–611.
doi :
10.1016/j.jgg.2015.09.010 .
PMID
26674378 .
This article incorporates text from the
United States National Library of Medicine , which is in the
public domain .