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Variability of lowest prices for Metformin 500 mg cap/tab. Median price ratio of the latest lowest generic price over the
MSH international reference price for Metformin 500 mg cap/tab, according to WHO/HAI methodology in 2015 or latest data. Prices below 100% are cheaper than the
international reference price.[1][2]
Graphs are unavailable due to technical issues. There is more info on
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Originator brand versus lowest generic prices for Metformin 500 mg cap/tab. Median price ratio of the latest lowest generic price or originator brand price over the
MSH international reference price for Metformin 500 mg cap/tab, according to WHO/HAI methodology. Prices below 100% are cheaper than the
international reference price.[1][2]
In the WHO/HAI systematic methodology, the same provider of international reference unit price "must be used for all medicines surveyed – global, regional and supplementary", to ensure a consistent basis for comparison.[1]: 38
Some authors criticized the MPR, as it can be skewed by the international reference price. For example, a 10% MPR for a $10 reference price yields an absolute price variation of $1, whereas for a $200 reference price the variation would be $20.[4] To solve this issue, the WHO/HAI recommend to check the international reference price when very high or low MPR variations are observed.[1]: 41
The MPR has been used in several studies investigating the availability and variation of medication prices,[5] and the effects of various medication pricing policies.[6]
The HAI maintains a regularly updated database of worldwide MPR surveys.[1]: 7 [2]