MDR may refer to:

• MDR1, an ATP-dependent cellular efflux pump affording multiple drug resistance
• Mammalian diving reflex
• Medical device reporting
• Multiple drug resistance, when a microorganism has become resistant to multiple drugs

• Managed detection and response, a type of computer managed security service
• Massive Data Repository, a data storage facility for the United States' Intelligence Community
• Sony MDR-V6, a line of studio headphones designed by Sony
• Medical device reprocessing
• Memory data register, a hardware register where data to be transferred to/from memory are temporarily stored
• Mental dead reckoning
• Merchant discount rate, dues, fees, assessments, network charges and mark-ups that merchants are required to pay for accepting credit and debit cards
• Metadata registry, a central location in an organization where metadata definitions are stored and maintained in a controlled method
• Metadata repository, a database created to store metadata
• Mini D ribbon, a cable connector type
• Motion detection radar
• Multifactor dimensionality reduction, an algorithm for detecting interactions
• Desert Tech MDR, a bullpup rifle
• MDR, programming language

• Moldavian Democratic Republic, a state existing between 1917 and 1918, predecessor of modern Moldova
• mdr is the ISO 639 language code for the Mandar language
• M. D. Ramanathan (1923–1984), Indian singer known as MDR
• Mandatory declassification review, part of the process of removing the classification of a document
• Medical Device Regulation (EU2017/745), a 2017 European Union regulation covering medical devices
• Mitteldeutscher Rundfunk, German public broadcaster
• Mort de rire, a French expression for "dead of laughing" (equivalent to English LOL)
• Mouvement démocratique républicain ( Republican Democratic Movement), former political party of Rwanda
• Major district road in the state of Andhra Pradesh, India
• Movement for Democracy and Reconstruction, political party in Liberia
• Main Development Region, the area of the Atlantic Ocean in which the majority of its tropical cyclones form

• All pages with titles beginning with MDR
• All pages with titles containing MDR
• MD (disambiguation)
• MDRA (disambiguation)
• MRD (disambiguation)

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