![]() Lisinopril (top) and hydrochlorothiazide (bottom) | |
Combination of | |
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Lisinopril | ACE inhibitor |
Hydrochlorothiazide | Thiazide diuretic |
Clinical data | |
Trade names | Zestoretic, Prinzide, others |
Other names | lisinopril/hctz |
AHFS/ Drugs.com | Micromedex Detailed Consumer Information |
MedlinePlus | a601070 |
License data | |
Pregnancy category |
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Routes of administration | By mouth |
ATC code | |
Legal status | |
Legal status | |
Identifiers | |
CAS Number | |
KEGG | |
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Lisinopril/hydrochlorothiazide, sold under the brand name Zestoretic among others, is a fixed-dose combination medication used for the treatment of high blood pressure (hypertension). [2] It contains lisinopril, an ACE inhibitor, and hydrochlorothiazide, a diuretic. [2] [3] Typically, it becomes an option once a person is doing well on the individual components. [4] It is taken by mouth. [3]
Common side effects include dizziness, headache, cough, and feeling tired. [2] Severe side effects may include angioedema and low blood pressure. [2] Use during pregnancy may harm the baby. [2]
The combination was approved for medical use in the United States in 1989. [3] It is on the World Health Organization's List of Essential Medicines. [5] It is available as a generic medication. [4] In 2021, it was the 51st most commonly prescribed medication in the United States, with more than 12 million prescriptions. [6] [7]
Lisinopril/hydrochlorothiazide is indicated for the treatment of hypertension, to lower blood pressure. [2]
The US Food and Drug Administration prescription label for the combination contains a boxed warning about harm to the baby. [2]