Species within this genus inhabit rocky fast-flowing parts of unpolluted and unimpounded mid-sized rivers in the American mid
South and the southern
Midwest. Species in the subgenus Mudalia inhabit rivers and creeks in the
Atlantic drainage.
Species
Species within the genus Leptoxis include:[2]
Those that are extinct are marked with a dagger †.
^(in French)Rafinesque C. S. (1819). "Prodrome de 70 nouveaux Genres d'Animaux découverts dans l'intérieur des États-Unis d'Amérique, durant l'année 1818". Journal de Physique, de Chimie et d'Histoire Naturelle88: 417-429. Leptoxis is on
page 424.