From Wikipedia, the free encyclopedia
Protein-coding gene in humans
Lin-7 homolog A is a
protein that in humans is encoded by the LIN7A
gene .
[5]
[6]
[7]
Interactions
LIN7A has been shown to
interact with:
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000111052 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000019906 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Jo K, Derin R, Li M, Bredt DS (Jun 1999).
"Characterization of MALS/Velis-1, -2, and -3: a family of mammalian LIN-7 homologs enriched at brain synapses in association with the postsynaptic density-95/NMDA receptor postsynaptic complex" . J Neurosci . 19 (11): 4189–99.
doi :
10.1523/JNEUROSCI.19-11-04189.1999 .
PMC
6782594 .
PMID
10341223 .
^ Bohl J, Brimer N, Lyons C, Vande Pol SB (Mar 2007).
"The stardust family protein MPP7 forms a tripartite complex with LIN7 and DLG1 that regulates the stability and localization of DLG1 to cell junctions" . J Biol Chem . 282 (13): 9392–400.
doi :
10.1074/jbc.M610002200 .
PMID
17237226 .
^
"Entrez Gene: LIN7A lin-7 homolog A (C. elegans)" .
^
a
b
c Leonoudakis D, Conti LR, Radeke CM, McGuire LM, Vandenberg CA (Apr 2004).
"A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels" . J. Biol. Chem . 279 (18): 19051–63.
doi :
10.1074/jbc.M400284200 .
PMID
14960569 .
^ Borg JP, Straight SW, Kaech SM, de Taddéo-Borg M, Kroon DE, Karnak D, Turner RS, Kim SK, Margolis B (Nov 1998).
"Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting" . J. Biol. Chem . 273 (48): 31633–6.
doi :
10.1074/jbc.273.48.31633 .
PMID
9822620 .
^ Leonoudakis D, Conti LR, Anderson S, Radeke CM, McGuire LM, Adams ME, Froehner SC, Yates JR, Vandenberg CA (May 2004).
"Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins" . J. Biol. Chem . 279 (21): 22331–46.
doi :
10.1074/jbc.M400285200 .
PMID
15024025 .
Further reading
Rousset R, Fabre S, Desbois C, Bantignies F, Jalinot P (1998).
"The C-terminus of the HTLV-1 Tax oncoprotein mediates interaction with the PDZ domain of cellular proteins" . Oncogene . 16 (5): 643–54.
doi :
10.1038/sj.onc.1201567 .
PMID
9482110 .
Butz S, Okamoto M, Südhof TC (1998).
"A tripartite protein complex with the potential to couple synaptic vesicle exocytosis to cell adhesion in brain" . Cell . 94 (6): 773–82.
doi :
10.1016/S0092-8674(00)81736-5 .
PMID
9753324 .
S2CID
12465062 .
Borg JP, Straight SW, Kaech SM, de Taddéo-Borg M, Kroon DE, Karnak D, Turner RS, Kim SK, Margolis B (1998).
"Identification of an evolutionarily conserved heterotrimeric protein complex involved in protein targeting" . J. Biol. Chem . 273 (48): 31633–6.
doi :
10.1074/jbc.273.48.31633 .
PMID
9822620 .
Borg JP, Lõpez-Figueroa MO, de Taddèo-Borg M, Kroon DE, Turner RS, Watson SJ, Margolis B (1999).
"Molecular analysis of the X11-mLin-2/CASK complex in brain" . J. Neurosci . 19 (4): 1307–16.
doi :
10.1523/JNEUROSCI.19-04-01307.1999 .
PMC
6786035 .
PMID
9952408 .
Perego C, Vanoni C, Villa A, Longhi R, Kaech SM, Fröhli E, Hajnal A, Kim SK, Pietrini G (1999).
"PDZ-mediated interactions retain the epithelial GABA transporter on the basolateral surface of polarized epithelial cells" . EMBO J . 18 (9): 2384–93.
doi :
10.1093/emboj/18.9.2384 .
PMC
1171321 .
PMID
10228153 .
Kamberov E, Makarova O, Roh M, Liu A, Karnak D, Straight S, Margolis B (2000).
"Molecular cloning and characterization of Pals, proteins associated with mLin-7" . J. Biol. Chem . 275 (15): 11425–31.
doi :
10.1074/jbc.275.15.11425 .
PMID
10753959 .
Tseng TC, Marfatia SM, Bryant PJ, Pack S, Zhuang Z, O'Brien JE, Lin L, Hanada T, Chishti AH (2001). "VAM-1: a new member of the MAGUK family binds to human Veli-1 through a conserved domain". Biochim. Biophys. Acta . 1518 (3): 249–59.
doi :
10.1016/s0167-4781(01)00191-9 .
PMID
11311936 .
Harris BZ, Venkatasubrahmanyam S, Lim WA (2002).
"Coordinated folding and association of the LIN-2, -7 (L27) domain. An obligate heterodimerization involved in assembly of signaling and cell polarity complexes" . J. Biol. Chem . 277 (38): 34902–8.
doi :
10.1074/jbc.M205856200 .
PMID
12110687 .
Hori K, Konno D, Maruoka H, Sobue K (2003).
"MALS is a binding partner of IRSp53 at cell-cell contacts" . FEBS Lett . 554 (1–2): 30–4.
doi :
10.1016/S0014-5793(03)01074-3 .
PMID
14596909 .
S2CID
30329043 .
Leonoudakis D, Conti LR, Radeke CM, McGuire LM, Vandenberg CA (2004).
"A multiprotein trafficking complex composed of SAP97, CASK, Veli, and Mint1 is associated with inward rectifier Kir2 potassium channels" . J. Biol. Chem . 279 (18): 19051–63.
doi :
10.1074/jbc.M400284200 .
PMID
14960569 .
Leonoudakis D, Conti LR, Anderson S, Radeke CM, McGuire LM, Adams ME, Froehner SC, Yates JR, Vandenberg CA (2004).
"Protein trafficking and anchoring complexes revealed by proteomic analysis of inward rectifier potassium channel (Kir2.x)-associated proteins" . J. Biol. Chem . 279 (21): 22331–46.
doi :
10.1074/jbc.M400285200 .
PMID
15024025 .
Olsen O, Wade JB, Morin N, Bredt DS, Welling PA (2005). "Differential localization of mammalian Lin-7 (MALS/Veli) PDZ proteins in the kidney". Am. J. Physiol. Renal Physiol . 288 (2): F345–52.
doi :
10.1152/ajprenal.00235.2004 .
PMID
15494546 .
S2CID
36221552 .
Dode L, Andersen JP, Raeymaekers L, Missiaen L, Vilsen B, Wuytack F (2006).
"Functional comparison between secretory pathway Ca2+/Mn2+-ATPase (SPCA) 1 and sarcoplasmic reticulum Ca2+-ATPase (SERCA) 1 isoforms by steady-state and transient kinetic analyses" . J. Biol. Chem . 280 (47): 39124–34.
doi :
10.1074/jbc.M506181200 .
PMID
16192278 .