Ijeoma Uchegbu is a Nigerian-British Professor of
Pharmacy at
University College London where she held the position of Pro-Vice Provost for
Africa and the Middle East. She is the Chief Scientific Officer of Nanomerics, a pharmaceutical
nanotechnology company specialising in drug delivery solutions for poorly water-soluble drugs, nucleic acids and peptides. She is also a Governor of the Wellcome, a large biomedical research charity.
Apart from her highly cited scientific research in Pharmaceutical
Nanoscience,[1] Uchegbu is also known for her work in science
public engagement and
equality and diversity in
Science,
Technology,
Engineering and
Mathematics (STEM).[2][3]
In December 2023, it was announced that she will become President of
Wolfson College, Cambridge in October 2024.[4]
Education and early career
Uchegbu grew up in Hackney and South East
Nigeria.[5] She studied pharmacy at the
University of Benin, graduating in 1981, and earned her master's degree at the
University of Lagos.[6] She could not complete a PhD in Nigeria due to infrastructure difficulties in the 80s.
"I came into science simply because after training as a pharmacist I wanted something a little bit more challenging to do. I thought that being a researcher would be a great place to start. As I did my pharmacy degree at Nigeria’s University of Benin, I did give research a try in Nigeria, but the infrastructure difficulties in the eighties made this virtually impossible. I came back to the UK, having emigrated 17 years earlier from the UK to Nigeria and started looking around for opportunities."[7]
She moved back to the UK and completed her postgraduate studies at the
University of London, graduating with a PhD in 1997. She was appointed a lecturer at the
University of Strathclyde from 2002-2004.
Uchegbu has been elected President of Wolfson College, Cambridge and will take up the post commencing 1st October 2024. [8]
Research
Uchegbu was made a Chair in Drug Delivery at the
University of Strathclyde in 2002. Here she worked on polymer self-assembly, identifying materials that could form stable
nanosystems.[9] She demonstrated that polymer molecular weight could be used to control the size of vesicles.[10] She joined
University College London in 2006 as a Chair in Pharmaceutical Nanoscience at the School of Pharmacy.[11][12] Uchegbu leads a research group that investigate molecular design and dosage of pharmaceuticals.[13] She has designed polymers that self-assemble into nanoparticles with the appropriate properties to transport drugs.[13] She explores how nanoparticles can be used for drug delivery.[14] Uchegbu holds several patents for drug delivery,[15][16][17][18][19][20][21][22] and biocompatible polymers.[23][24][25] Her pharmaceuticals deliver genes and
siRNA to tumours and peptides to the brain as well as encouraging the absorption of hydrophobic drugs using nanoparticles.[26] She is exploring how nanomedicine can be used to treat brain tumours.[27] In 2018 she was part of a £5.7 million
Engineering and Physical Sciences Research Council grant, Raman Nano
theranostics, that will use gold nanoparticles to identify disease and light to destroy diseased cells.[28] She also works with magnetic
nanoparticles.[29][30]
Nanomerics
In 2010 Uchegbu founded
Nanomerics with Andreas Schätzlein.[31]Nanomerics is a pharmaceutical company that uses nanotechnology platforms to develop medicine. Uchegbu is the Chief Scientific Officer of Nanomerics.[9]Nanomerics are developing structures that can transport antibodies that can cross the
blood–brain barrier.[32]Nanomerics develop molecular envelope technology nanoparticles from amphiphilic polymers that self-assemble.[33] She won the
Royal Society of Chemistry Emerging Technologies prize for their molecular envelope technology in 2017.[34] She licensed the medicine NM133 to
Iacta Pharmaceuticals in 2017.[33] NM133 contains
cyclosporine A and can be used to treat dry eye.[33]
In 2015 Uchegbu was appointed Pro-Vice Provost for Africa and the Middle East.[39][40] She chairs the Africa and Middle East regional network at
University College London, building partnerships and starting collaborative teams, welcoming international visitors and supporting student recruitment.[41]
Public Engagement and Equality and Diversity
Uchegbu is involved in public engagement and
science communication and is featured in BBC Woman's Hour discussing her research into how nano particles can be used to help deliver drugs to the body[42] and taken part in
Soapbox Science an international science outreach programme promoting women scientists and the work they do to members of the public.[7]
Uchegbu is also involved in equality and diversity activities and programmes, acting as the UCL Provost's Envoy for Race Equality[3] and featuring as the only Black British Role Model for the
Women's Engineering Society.[2] She also serves on the
University College London Race Equality Charter self-assessment team.[43][44] She is part of the Black Female Professors Forum, representing 1 of the 55 female professors of colour and 1 of the 25 Black female professors in the UK in 2017.[45][46]
Books
2000 Synthetic Surfactant Vesicles: Niosomes and Other Non-phospholipid Vesicular Systems: 11 (Drug Targeting and Delivery)[47]
^Wang, Wei; McConaghy, Anne Marie; Tetley, Laurence; Uchegbu, Ijeoma F. (February 2001). "Controls on Polymer Molecular Weight May Be Used To Control the Size of Palmitoyl Glycol Chitosan Polymeric Vesicles". Langmuir. 17 (3): 631–636.
doi:
10.1021/la001078w.
ISSN0743-7463.
^Uchegbu, L. F. (2000-02-01). Synthetic Surfactant Vesicles: Niosomes and Other Non-Phospholipid Vesicular Systems (1st ed.). Amsterdam: CRC Press.
ISBN9789058230119.
^Uchegbu, Ijeoma F.; Schatzlein, Andreas G., eds. (2006-05-19). Polymers in Drug Delivery (1st ed.). Boca Raton, Fla.: CRC Press.
ISBN9780849325335.