From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Inositol hexakisphosphate kinase 1 is an
enzyme that in humans is encoded by the IP6K1
gene .
[5]
This gene encodes a protein that belongs to the inositol phosphokinase (IPK) family. This protein is likely responsible for the conversion of inositol hexakisphosphate (InsP6) to diphosphoinositol pentakisphosphate (InsP7/PP-InsP5). It may also convert 1,3,4,5,6-pentakisphosphate (InsP5) to PP-InsP4. Alternative splicing occurs for this gene; however, the full-length nature of all transcript variants has not yet been described.
[5]
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S2CID
22338269 .
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PMID
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S2CID
6834292 .
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PMID
10574768 .
S2CID
15311443 .
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doi :
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PMC
139241 .
PMID
12477932 .
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"The IHPK1 gene is disrupted at the 3p21.31 breakpoint of t(3;9) in a family with type 2 diabetes mellitus" . J. Hum. Genet . 49 (7): 360–5.
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PMID
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Rual JF, Venkatesan K, Hao T, et al. (2005). "Towards a proteome-scale map of the human protein-protein interaction network". Nature . 437 (7062): 1173–8.
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PMID
16189514 .
S2CID
4427026 .