Immunoglobulin kappa locus, also known as IGK@, is a region on the p arm of human
chromosome 2, region 11.2 (2p11.2), that contains
genes for the kappa (κ)
light chains of
antibodies (or immunoglobulins).[2]
In humans the κ chain is coded for by
V (variable),
J (joining) and
C (constant) genes in this region.[3] These genes undergo
V(D)J recombination to generate a diverse repertoire of immunoglobulins.
Genes
The immunoglobulin kappa locus contains the following genes: