The Histiocyte Society is an international network of people that co-ordinate studies of the
histiocytoses, which it has divided into
Langerhans cell histiocytosis (class I) (previously known as
Hand–Schüller–Christian disease and histocytosis-X), non-Langerhans cell histiocytoses (class II), and malignant histiocytosis (class III).[1][2][3][4] They provided the criteria to definitively diagnose Langerhans cell histiocytosis.[5]