From Wikipedia, the free encyclopedia
Phagocytosis of blood cells
Micrograph showing hemophagocytosis in the
spleen.
H&E stain.
Hemophagocytosis is a dangerous form of
phagocytosis in which
histiocytes engulf
red blood cells,
white blood cells,
platelets, and their precursors
[1] in
bone marrow and other tissues.
It is part of the presentation of
hemophagocytic lymphohistiocytosis and
macrophage activation syndrome. It has also been seen at
autopsy of people who died of
COVID-19.
[2]
-
^
"Hemophagocytic Syndromes and Infection".
-
^ Satturwar, Swati; Fowkes, Mary; Farver, Carol; Wilson, Allecia M.; Eccher, Albino; Girolami, Ilaria; Pujadas, Elisabet; Bryce, Clare; Salem, Fadi; El Jamal, Siraj M.; Paniz-Mondolfi, Alberto; Petersen, Bruce; Gordon, Ronald E.; Reidy, Jason; Fraggetta, Filippo; Marshall, Desiree A.; Pantanowitz, Liron (2021).
"Postmortem Findings Associated With SARS-CoV-2". American Journal of Surgical Pathology (5): 587–603.
doi:
10.1097/PAS.0000000000001650.
ISSN
0147-5185.
PMC
8132567.