Hematoporphyrin (Photodyn, Sensibion) is a
porphyrin prepared from
hemin. It is a derivative of
protoporphyrin IX, where the two vinyl groups have been hydrated (converted to alcohols). It is a deeply colored solid that is usually encountered as a solution. Its
chemical structure was determined in 1900.[1]
It is used as a photosensitizer in
photodynamic therapy. Acetylation of hematoporphyrin followed by hydrolysis of the product of that reaction affords a mixture called hematoporphyrin derivative (HPD), which is also used in photodynamic therapy.[2]
^Strecker EA, Palmer HP, Braceland FJ (May 1934). "Hematoporphyrin as a Therapeutic Agent in the Psychoses". American Journal of Psychiatry. 90 (6): 1157–1173.
doi:
10.1176/ajp.90.6.1157.