Gregoria Apaza (June 23, 1751– September 5, 1782) was an Indigenous leader in Bolivia. [1] In 1781, she participated with her brother Julian Apaza ( Tupac Katari) and sister-in-law Bartolina Sisa in a major Indigenous revolt against Spanish colonial rule in Bolivia. [2] These Aymara leaders laid siege to the cities of La Paz and Sorata before being defeated and executed in 1782. [3] [4]