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GADV-protein world is a hypothetical stage of abiogenesis. GADV stands for the one letter codes of four amino acids, namely, glycine (G), alanine (A), aspartic acid (D) and valine (V), the main components of GADV proteins. In the GADV-protein world hypothesis, it is argued that the prebiotic chemistry before the emergence of genes involved a stage where GADV-proteins were able to pseudo-replicate. This hypothesis is contrary to the RNA world hypothesis. [1]
The GADV-protein world hypothesis was first proposed by Kenji Ikehara at Nara Women's University. It is supported by GNC-SNS primitive gene code hypothesis ( GNC hypothesis) also formulated by him. In the GNC hypothesis, the origin of the present standard genetic code is considered to be the GNC genetic code that includes the codons G GC, G CC, G AC, G UC, respectively coding glycine, alanine, aspartic acid, and valine; it also follows the SNS primitive genetic code that codes ten amino acids, where N denotes arbitrary four RNA bases and S denotes guanine (G) and cytosine (C).
The GADV hypothesis proposes these mechanisms: