German neuroscientist and neurologist
Friedhelm Christoph Hummel (born 1969 in
Laichingen , Germany) is a German
neuroscientist and
neurologist . A full professor at
École Polytechnique Fédérale de Lausanne , he is the Defitech Chair of Clinical Neuroengineering, and the head of the Hummel Laboratory at EPFL's School of Life Sciences.
[1]
[2] He also is an associate professor of clinical neuroscience at the
University of Geneva .
[3]
Career
Hummel studied medicine at
University of Tübingen and at
Bordeaux Segalen University , graduating in 1998. He then joined the Department of Neurology at the University of Tübingen as a medical resident and researcher.
[4] He earned his medical doctor degree in 2000 for his work on Plastische Veränderungen durch semantische klassische Konditionierung und ihre elektrokortikalen Korrelate: eine Studie langsamer Potentiale (Plastic changes through semantic classical conditioning and their electrocortical correlates: a study of slow potentials).
[5]
In 2003, he received a
Feodor Lynen award from the
Alexander von Humboldt Foundation to join Leonardo Cohen's Human Cortical Physiology and Neurorehabilitation Section (
NINDS ) at the
National Institutes of Health (NIH) at
Bethesda .
[6]
[7] There he worked on the first successful application of transcranial direct current stimulation (tDCS) in stroke patients.
[8] In 2005, he returned as researcher and medical resident to the Department of Neurology at Tübingen,
[9] and, in 2006, to the
University Medical Center Hamburg-Eppendorf to finish his residency.
[10] In 2006, he founded the Brain Imaging and Neurostimulation (BINS) Laboratory at Hamburg, became a certified in 2007,
[11]
[12] co-chairman at the Centre for Sleep Medicine in 2008, senior neurologist in 2013, and vice-director of the Department of neurology in 2013.
[13]
[14]
Since 2016 he holds the Defitech Chair for Clinical Neuroengineering as full professor, is the director of the Hummel Laboratory at the Centre for Neuroprosthetics (CNP) and the Brain Mind Institute (BMI), both at EPFL.
[1]
[2] Furthermore, he holds an associate professorship of clinical neuroscience at the University of Geneva.
[3]
Research
Hummel's research targets the fields of
systems and
translational clinical neuroscience with three main areas of focus.
The first focus is on using multimodal imaging and behavioral measures to study neuroplasticity, neuronal control of sensorimotor functions, learning, and cognitive functions in healthy and neurological disorders, such as stroke, mild cognitive impairment (MCI) or traumatic brain injury (TBI).
The second main focus is on developing innovative non-invasive interventional strategies based on neurotechnology,
[15]
[16]
[17] such as brain stimulation
[18]
[19] to support patients' residual functions and enhance recovery.
[20]
[21] He has been involved in the application of non-invasive brain stimulation in stroke.
[22]
[23]
The third focus is the use of multimodal imaging to predict outcome and course of recovery after a stroke (Koch et al. 2021 Brain; Egger et al. 2021 Stroke), a prerequisite for personalized treatment strategies.
[24]
[25]
His research has been featured in news outlets such as
NZZ ,
[26]
Le Nouvelliste ,
Physics World ,
[27]
Der Spiegel ,
[28] and
Focus .
[29]
Distinctions
Hummel is the recipient of the 2015 Felgenhauer Symposiums Prize of the German Neurological Society and the Felgenhauer Foundation;
[30] the 2013 prize of the German Society of Neurotraumatology and Clinical Neurorehabilitation;
[31] the 2010 Dr. Martini Prize;
[32] the 2005 Susanne Klein-Vogelbach Prize;
[33] 2005 Fellows Award for Research Excellence by the National Institutes of Health; and the 2003 Feodor Lynen Research Fellowship Award by the Alexander von Humboldt Foundation.
[31]
He is a member of the German Neurological Society,
[34] the
Society for Neuroscience , and the Society for the Neural Control of Movement.
[35]
Selected works
Nitsche, Michael A.; Cohen, Leonardo G.; Wassermann, Eric M.; Priori, Alberto; Lang, Nicolas; Antal, Andrea; Paulus, Walter; Hummel, Friedhelm; Boggio, Paulo S.; Fregni, Felipe; Pascual-Leone, Alvaro (July 2008).
"Transcranial direct current stimulation: State of the art 2008" . Brain Stimulation . 1 (3): 206–223.
doi :
10.1016/j.brs.2008.06.004 .
ISSN
1935-861X .
PMID
20633386 .
S2CID
16352598 .
Lefaucheur, Jean-Pascal; André-Obadia, Nathalie; Antal, Andrea; Ayache, Samar S.; Baeken, Chris; Benninger, David H.; Cantello, Roberto M.; Cincotta, Massimo; de Carvalho, Mamede; De Ridder, Dirk; Devanne, Hervé (November 2014).
"Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS)" . Clinical Neurophysiology . 125 (11): 2150–2206.
doi :
10.1016/j.clinph.2014.05.021 .
ISSN
1388-2457 .
PMID
25034472 .
S2CID
206798663 .
Gandiga, Prateek C.; Hummel, Friedhelm C.; Cohen, Leonardo G. (April 2006).
"Transcranial DC stimulation (tDCS): A tool for double-blind sham-controlled clinical studies in brain stimulation" . Clinical Neurophysiology . 117 (4): 845–850.
doi :
10.1016/j.clinph.2005.12.003 .
ISSN
1388-2457 .
PMID
16427357 .
S2CID
25934876 .
Hummel, F. (2005-01-05).
"Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke" . Brain . 128 (3): 490–499.
doi :
10.1093/brain/awh369 .
ISSN
1460-2156 .
PMID
15634731 .
Hummel, Friedhelm C; Cohen, Leonardo G (August 2006).
"Non-invasive brain stimulation: a new strategy to improve neurorehabilitation after stroke?" . The Lancet Neurology . 5 (8): 708–712.
doi :
10.1016/s1474-4422(06)70525-7 .
ISSN
1474-4422 .
PMID
16857577 .
S2CID
9509765 .
Pulvermüller, Friedemann; Härle, Markus; Hummel, Friedhelm (2001-08-01).
"Walking or Talking?: Behavioral and Neurophysiological Correlates of Action Verb Processing" . Brain and Language . 78 (2): 143–168.
doi :
10.1006/brln.2000.2390 .
ISSN
0093-934X .
PMID
11500067 .
S2CID
40912475 .
Sauseng, Paul; Klimesch, Wolfgang; Heise, Kirstin F.; Gruber, Walter R.; Holz, Elisa; Karim, Ahmed A.; Glennon, Mark; Gerloff, Christian; Birbaumer, Niels; Hummel, Friedhelm C. (2009).
"Brain Oscillatory Substrates of Visual Short-Term Memory Capacity" . Current Biology . 19 (21): 1846–1852.
doi :
10.1016/j.cub.2009.08.062 .
PMID
19913428 .
S2CID
13999952 .
Fridman, E. A.; Hanakawa, T.; Chung, M.; Hummel, F.; Leiguarda, R. C.; Cohen, L. G. (2004).
"Reorganization of the human ipsilesional premotor cortex after stroke" . Brain . 127 (4): 747–758.
doi :
10.1093/brain/awh082 .
PMID
14749291 .
Antal, A.; et al. (2017).
"Low intensity transcranial electric stimulation: Safety, ethical, legal regulatory and application guidelines" . Clinical Neurophysiology . 128 (9): 1774–1809.
doi :
10.1016/j.clinph.2017.06.001 .
PMC
5985830 .
PMID
28709880 .
Sauseng, P.; Hoppe, J.; Klimesch, W.; Gerloff, C.; Hummel, F. C. (2007). "Dissociation of sustained attention from central executive functions: Local activity and interregional connectivity in the theta range". European Journal of Neuroscience . 25 (2): 587–593.
doi :
10.1111/j.1460-9568.2006.05286.x .
PMID
17284201 .
S2CID
3487768 .
Duque, Julie; Hummel, Friedhelm; Celnik, Pablo; Murase, Nagako; Mazzocchio, Riccardo; Cohen, Leonardo G. (2005). "Transcallosal inhibition in chronic subcortical stroke". NeuroImage . 28 (4): 940–946.
doi :
10.1016/j.neuroimage.2005.06.033 .
PMID
16084737 .
S2CID
39285099 .
References
^
a
b
"Hummel Lab" . www.epfl.ch . Retrieved 2021-04-14 .
^
a
b
"Brexit: closer cooperation with the UK cannot replace participation in Horizon 2020 | ETH-Board" . www.ethrat.ch . Archived from
the original on 2021-01-09. Retrieved 2021-04-15 .
^
a
b
"Friedhelm Hummel | Campus Biotech" . www.campusbiotech.ch . Retrieved 2021-04-15 .
^ Rau, Cornelia; Plewnia, Christian; Hummel, Friedhelm; Gerloff, Christian (2003-10-01).
"Event-related desynchronization and excitability of the ipsilateral motor cortex during simple self-paced finger movements" . Clinical Neurophysiology . 114 (10): 1819–1826.
doi :
10.1016/S1388-2457(03)00174-3 .
ISSN
1388-2457 .
PMID
14499743 .
S2CID
39272563 .
^ Hummel, Friedhelm C. (2000).
Plastische Veränderungen durch semantische klassische Konditionierung und ihre elektrokortikalen Korrelate eine Studie langsamer Potentiale . Tübingen. {{
cite book }}
: CS1 maint: location missing publisher (
link )
^ Fridman, E. A. (2004-01-14).
"Reorganization of the human ipsilesional premotor cortex after stroke" . Brain . 127 (4): 747–758.
doi :
10.1093/brain/awh082 .
ISSN
1460-2156 .
PMID
14749291 .
^ Hummel, F. (2005-01-05).
"Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke" . Brain . 128 (3): 490–499.
doi :
10.1093/brain/awh369 .
ISSN
1460-2156 .
PMID
15634731 .
^ Hummel, Friedhelm C; Cohen, Leonardo G (August 2006).
"Non-invasive brain stimulation: a new strategy to improve neurorehabilitation after stroke?" . The Lancet Neurology . 5 (8): 708–712.
doi :
10.1016/s1474-4422(06)70525-7 .
ISSN
1474-4422 .
PMID
16857577 .
S2CID
9509765 .
^ Gandiga, Prateek C.; Hummel, Friedhelm C.; Cohen, Leonardo G. (April 2006).
"Transcranial DC stimulation (tDCS): A tool for double-blind sham-controlled clinical studies in brain stimulation" . Clinical Neurophysiology . 117 (4): 845–850.
doi :
10.1016/j.clinph.2005.12.003 .
PMID
16427357 .
S2CID
25934876 .
^ Heise, K.-F; Gerloff, C; Hummel, F (September 2007).
"Nicht invasive kortikale Stimulation als adjuvante Therapie zur Unterstützung der funktionellen Erholung nach Schlaganfall" . Physioscience (in German). 3 (3): 99–108.
doi :
10.1055/s-2007-963363 .
ISSN
1860-3092 .
S2CID
260370328 .
^ Nitsche, Michael A.; Cohen, Leonardo G.; Wassermann, Eric M.; Priori, Alberto; Lang, Nicolas; Antal, Andrea; Paulus, Walter; Hummel, Friedhelm; Boggio, Paulo S.; Fregni, Felipe; Pascual-Leone, Alvaro (July 2008).
"Transcranial direct current stimulation: State of the art 2008" . Brain Stimulation . 1 (3): 206–223.
doi :
10.1016/j.brs.2008.06.004 .
PMID
20633386 .
S2CID
16352598 .
^ Sauseng, Paul; Klimesch, Wolfgang; Heise, Kirstin F.; Gruber, Walter R.; Holz, Elisa; Karim, Ahmed A.; Glennon, Mark; Gerloff, Christian; Birbaumer, Niels; Hummel, Friedhelm C. (2009-11-17).
"Brain Oscillatory Substrates of Visual Short-Term Memory Capacity" . Current Biology . 19 (21): 1846–1852.
doi :
10.1016/j.cub.2009.08.062 .
ISSN
0960-9822 .
PMID
19913428 .
S2CID
13999952 .
^ Hummel, Friedhelm Christoph; Gerloff, Christian (2011).
"Zukunft der Neuromodulation" . Handfunktionsstörungen in der Neurologie . Retrieved 2021-04-15 .
^ Lefaucheur, Jean-Pascal; André-Obadia, Nathalie; Antal, Andrea; Ayache, Samar S.; Baeken, Chris; Benninger, David H.; Cantello, Roberto M.; Cincotta, Massimo; de Carvalho, Mamede; De Ridder, Dirk; Devanne, Hervé (November 2014).
"Evidence-based guidelines on the therapeutic use of repetitive transcranial magnetic stimulation (rTMS)" . Clinical Neurophysiology . 125 (11): 2150–2206.
doi :
10.1016/j.clinph.2014.05.021 .
PMID
25034472 .
S2CID
206798663 .
^ Coscia, Martina; Wessel, Maximilian J; Chaudary, Ujwal; Millán, José del R; Micera, Silvestro; Guggisberg, Adrian; Vuadens, Philippe; Donoghue, John; Birbaumer, Niels; Hummel, Friedhelm C (2019-07-01).
"Neurotechnology-aided interventions for upper limb motor rehabilitation in severe chronic stroke" . Brain . 142 (8): 2182–2197.
doi :
10.1093/brain/awz181 .
ISSN
0006-8950 .
PMC
6658861 .
PMID
31257411 .
^ Micera, Silvestro; Caleo, Matteo; Chisari, Carmelo; Hummel, Friedhelm C.; Pedrocchi, Alessandra (2020-02-19).
"Advanced Neurotechnologies for the Restoration of Motor Function" . Neuron . 105 (4): 604–620.
doi :
10.1016/j.neuron.2020.01.039 .
hdl :
11311/1131435 .
ISSN
0896-6273 .
PMID
32078796 .
^ Raffin, Estelle; Salamanca-Giron, Roberto F.; Hummel, Friedhelm Christoph (2020-01-01).
"Perspectives: Hemianopia—Toward Novel Treatment Options Based on Oscillatory Activity?" . Neurorehabilitation and Neural Repair . 34 (1): 13–25.
doi :
10.1177/1545968319893286 .
ISSN
1545-9683 .
PMID
31858874 .
^ Wessel, Maximilian J.; Draaisma, Laurijn R.; de Boer, Anne F. W.; Park, Chang-hyun; Maceira-Elvira, Pablo; Durand-Ruel, Manon; Koch, Philipp J.; Morishita, Takuya; Hummel, Friedhelm C. (2020-07-08).
"Cerebellar transcranial alternating current stimulation in the gamma range applied during the acquisition of a novel motor skill" . Scientific Reports . 10 (1): 11217.
Bibcode :
2020NatSR..1011217W .
doi :
10.1038/s41598-020-68028-9 .
ISSN
2045-2322 .
PMC
7343806 .
PMID
32641706 .
^ Salamanca-giron, Roberto F.; Raffin, Estelle; Zandvliet, Sarah B.; Seeber, Martin; Michel, Christoph M.; Sauseng, Paul; Huxlin, Krystel R.; Hummel, Friedhelm C. (2021-10-15).
"Enhancing visual motion discrimination by desynchronizing bifocal oscillatory activity" . NeuroImage . 240 : 118299.
doi :
10.1016/j.neuroimage.2021.118299 .
ISSN
1053-8119 .
PMID
34171500 .
^ Raffin, Estelle; Hummel, Friedhelm C. (2018-08-01).
"Restoring Motor Functions After Stroke: Multiple Approaches and Opportunities" . The Neuroscientist . 24 (4): 400–416.
doi :
10.1177/1073858417737486 .
ISSN
1073-8584 .
PMID
29283026 .
S2CID
206658560 .
^ Wessel, Maximilian J.; Hummel, Friedhelm C. (2018-06-01).
"Non-invasive Cerebellar Stimulation: a Promising Approach for Stroke Recovery?" . The Cerebellum . 17 (3): 359–371.
doi :
10.1007/s12311-017-0906-1 .
ISSN
1473-4230 .
PMID
29243202 .
S2CID
255587313 .
^ Hummel, F. (2005-01-05).
"Effects of non-invasive cortical stimulation on skilled motor function in chronic stroke" . Brain . 128 (3): 490–499.
doi :
10.1093/brain/awh369 .
ISSN
1460-2156 .
PMID
15634731 .
^ Hummel, Friedhelm C.; Cohen, Leonardo G. (2006-08-01).
"Non-invasive brain stimulation: a new strategy to improve neurorehabilitation after stroke?" . The Lancet Neurology . 5 (8): 708–712.
doi :
10.1016/S1474-4422(06)70525-7 .
ISSN
1474-4422 .
PMID
16857577 .
S2CID
9509765 .
^ Koch, Philipp J; Park, Chang-Hyun; Girard, Gabriel; Beanato, Elena; Egger, Philip; Evangelista, Giorgia Giulia; Lee, Jungsoo; Wessel, Maximilian J; Morishita, Takuya; Koch, Giacomo; Thiran, Jean-Philippe (2021-07-01).
"The structural connectome and motor recovery after stroke: predicting natural recovery" . Brain . 144 (7): 2107–2119.
doi :
10.1093/brain/awab082 .
ISSN
0006-8950 .
PMC
8370413 .
PMID
34237143 .
^ Egger, Philip; Evangelista, Giorgia G.; Koch, Philipp J.; Park, Chang-Hyun; Levin-Gleba, Laura; Girard, Gabriel; Beanato, Elena; Lee, Jungsoo; Choirat, Christine; Guggisberg, Adrian G.; Kim, Yun-Hee (2021-06-01).
"Disconnectomics of the Rich Club Impacts Motor Recovery After Stroke" . Stroke . 52 (6): 2115–2124.
doi :
10.1161/STROKEAHA.120.031541 .
PMID
33902299 .
^ Geiser, Eveline (2021-07-15).
"Wo Ärzte abwarten müssen, kann künstliche Intelligenz eine Prognose stellen" . Neue Zürcher Zeitung . Retrieved 2021-09-01 .
^
"Mapping the brain's neural connections can predict recovery after stroke" . Physics World . 2021-07-13. Retrieved 2021-09-01 .
^ SPIEGEL, Susanne Schäfer, DER (23 April 2015).
"Warum ein Schlag auf den Musikknochen so weh tut" . Der Spiegel (in German). Retrieved 2021-09-01 . {{
cite news }}
: CS1 maint: multiple names: authors list (
link )
^
"Stimulation von Hirnarealen" . FOCUS Online (in German). Retrieved 2021-09-01 .
^
"Awards (2014 - 2015)" . hahn-institute.de . Retrieved 2021-04-15 .
^
a
b
"Third congress on NeuroRehabilitation and Neural Repair" (PDF) . NeuroRehabilitation and Neural Repair . Retrieved 2021-04-15 .
^
"Dr. Martini-Preis | Dr.-Martini-Stiftung" . 2016-10-23. Archived from
the original on 2016-10-23. Retrieved 2021-04-15 .
^
"SKV-Preis" . FBL FUNCTIONAL KINETICS (in German). Retrieved 2021-04-15 .
^
"Preise und Ehrungen der DGN auf dem Kongress 2015 - Deutsche Gesellschaft für Neurologie e. V." Deutsche Gesellschaft für Neurologie (in German). Retrieved 2021-04-15 .
^
"29th NCM Annual Meeting" (PDF) . Neural Control of Movement Society . Retrieved 2021-04-15 .
External links
International National Academics