DescriptionMutations in diffuse intrinsic pontine glioma samples from several anatomical locations - Ncomms11185-f1.jpg
English: Mutations in diffuse intrinsic pontine glioma (DIPG) samples from several anatomical locations. Samples representing different anatomical locations within each patient are represented in columns. The mutations (in rows) were selected based on published datasets in paediatric glioblastoma and specifically DIPG. Mutations were divided into two subgroups; driver mutations which are essential for tumour initiation/maintenance and accessory driver mutations, which can further promote and accelerate tumour growth, but are not absolutely essential for tumour initiation or maintenance.
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Spatial and temporal homogeneity of driver mutations in diffuse intrinsic pontine glioma
Hamid Nikbakht, Eshini Panditharatna, Leonie G. Mikael, Rui Li, Tenzin Gayden, Matthew Osmond, Cheng-Ying Ho, Madhuri Kambhampati, Eugene I. Hwang, Damien Faury, Alan Siu, Simon Papillon-Cavanagh, Denise Bechet, Keith L. Ligon, Benjamin Ellezam, Wendy J. Ingram, Caedyn Stinson, Andrew S. Moore, Katherine E. Warren, Jason Karamchandani, Roger J. Packer, Nada Jabado, Jacek Majewski & Javad Nazarian
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