| Enterovirus 5′ cloverleaf cis-acting replication element | |
|---|---|
 Predicted
secondary structure and
sequence conservation of Entero_5_CRE | |
| Identifiers | |
| Symbol | Entero_5_CRE |
| Rfam | RF00386 |
| Other data | |
| RNA type | Cis-reg |
| Domain(s) | Viruses |
| SO | SO:0000233 |
| PDB structures | PDBe |
The Enterovirus 5′ cloverleaf cis-acting replication element is an RNA element found in the 5′ UTR of Enterovirus genomes. The element has a cloverleaf like secondary structure and is known to be a multifunctional cis-acting replication element (CRE), required for the initiation of negative strand RNA synthesis. [1]
- ^ Barton DJ, O'Donnell BJ, Flanegan JB (March 2001). "5′ cloverleaf in poliovirus RNA is a cis-acting replication element required for negative-strand synthesis". The EMBO Journal. 20 (6): 1439–1448. doi: 10.1093/emboj/20.6.1439. PMC 145522. PMID 11250909.
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