From Wikipedia, the free encyclopedia
The E-site is the third and final
binding site for
t-RNA in the
ribosome during
translation , a part of
protein synthesis .
[1] The "E" stands for exit, and is accompanied by the
P-site (for peptidyl) which is the second binding site, and the
A-site (aminoacyl), which is the first binding site. It is involved in
cellular processes .
[2]
[3]
References
^ Chen, C.; Stevens, B.; Kaur, J.; Smilansky, Z.; Cooperman, B. S.; Goldman, Y. E. (2011-10-03).
"Allosteric vs. spontaneous exit-site (E-site) tRNA dissociation early in protein synthesis" . Proceedings of the National Academy of Sciences . 108 (41): 16980–16985.
Bibcode :
2011PNAS..10816980C .
doi :
10.1073/pnas.1106999108 .
ISSN
0027-8424 .
PMC
3193197 .
PMID
21969541 .
^ Kirillov, S., Makarov, E., & Semenkov, Y. (1983). Quantitative study of interaction of deacylated tRNA with Escherichia coli ribosomes. FEBS Letters, 157(1), 91-94.
doi :
10.1016/0014-5793(83)81122-3
^ dx.doi.org .
doi :
10.17658/issn.2058-5462/issue-23/efisher/p1
http://dx.doi.org/10.17658/issn.2058-5462/issue-23/efisher/p1 . Retrieved 2024-01-26 .
Sergiev, Petr V.; Lesnyak, Dmitry V.; Kiparisov, Sergey V.; Burakovsky, Dmitry E.; Leonov, Andrei A.; Bogdanov, Alexey A.; Brimacombe, Richard; Dontsova, Olga A. (2005).
"Function of the ribosomal E-site: a mutagenesis study" . Nucleic Acids Research . 33 (18): 6048–6056.
doi :
10.1093/nar/gki910 .
ISSN
0305-1048 .
PMC
1266066 .
PMID
16243787 .
Chen, Chunlai; Stevens, Benjamin; Kaur, Jaskiran; Smilansky, Zeev; Cooperman, Barry S.; Goldman, Yale E. (2011-10-11).
"Allosteric vs. spontaneous exit-site (E-site) tRNA dissociation early in protein synthesis" . Proceedings of the National Academy of Sciences . 108 (41): 16980–16985.
Bibcode :
2011PNAS..10816980C .
doi :
10.1073/pnas.1106999108 .
ISSN
0027-8424 .
PMC
3193197 .
PMID
21969541 .
Molecular Biology of the Gene, 7th Edition, James D. Watson, Tania A. Baker,Stephen P. Bell,Alexander Gann, Michael Levine,Richard Losick, ©2014 Pearson