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Defiant may refer to:

• Defiant (Star Trek: Deep Space Nine), an episode of the series Star Trek: Deep Space Nine
• Star Trek: Defiant, comic book by IDW
• USS Defiant, a starship in Star Trek: Deep Space Nine and in the film Star Trek: First Contact
• USS Defiant (NCC-1764), sister ship to the Enterprise in the Star Trek: The Original Series episode " The Tholian Web"

• Boulton Paul Defiant, a British fighter aircraft of World War 2
• Defiant 300, a prototype aircraft of the Philippines
• GWR 4073 Class 5080 Defiant, a Great Western Railway locomotive
• Rutan Defiant, an aircraft designed by Burt Rutan
• Defiant (YT-804), a Valiant-class tugboat launched 2010
• Sikorsky–Boeing SB-1 Defiant, an American compound helicopter

• Defiant, a 2006 album by Vice Squad
• Defiant (G.I. Joe), a fictional space shuttle complex in the toy line G.I. Joe: A Real American Hero
• Defiant Comics, a comic book publishing imprint
• Defiant Theatre, an American theatre company based in Chicago
• Defiant (film), a 2023 documentary film
• The Defiant, a World War II memoir by Shalom Yoran
• The Defiant (band), American punk rock supergroup
• The Sandpit Generals, a 1971 American film also released as The Defiant
• H.M.S. Defiant, a 1962 film
• Toronto Defiant, a Canadian esports team

• Defiance (disambiguation)
• Defy (disambiguation)
• Disobedience

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