In biochemistry, the Corey-Pauling rules are a set of three basic statements that govern the secondary nature of proteins, in particular, the CO-NH peptide link. They were originally proposed by
Robert Corey and
Linus Pauling.[1]
The rules are as follows:
The atoms in a peptide link all lie on the same plane.
The nitrogen, hydrogen, and oxygen atoms in a hydrogen bond are approximately in a straight line.
The carbon-oxygen and nitrogen-hydrogen groups are all involved in bonding.
References
^John Daintith, ed. (2008). A Dictionary of Chemistry (6th ed.). Oxford University Press.
ISBN9780199204632.