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American geneticist
Chengcang Charles Wu is a Chinese-born American scientist with expertise in the fields of genetics, bioinformatics, and genomics, particularly large fragment DNA cloning and BAC (Bacterial Artificial Chromosome) library technologies.
[1]
[2]
[3]
[4]
Wu is the main contributor of the first soybean physical map.
[5] He is also one of the inventors of plant artificial chromosomes,
[4] Fungal Artificial Chromosomes and related technologies.
[1]
Biotechnology involvement
Wu was the founding vice president of Lucigen Corporation. In 2013, Wu Founded Intact Genomics, Inc. in St. Louis Missouri.
Anhui Agricultural University, China , B.S., Biology. M.S., Genetics
Iwate University, Japan , Ph.D, Bioenvironmental Science
^
a
b Clevenger, Kenneth D; Bok, Jin Woo; Ye, Rosa; Miley, Galen P; Verdan, Maria H; Velk, Thomas; Chen, Cynthia; Yang, KaHoua; Robey, Matthew T (2017-06-12).
"A scalable platform to identify fungal secondary metabolites and their gene clusters" . Nature Chemical Biology . 13 (8): 895–901.
doi :
10.1038/nchembio.2408 .
PMC
5577364 .
PMID
28604695 .
^ Alexeyenko, Andrey; Nystedt, Björn; Vezzi, Francesco; Sherwood, Ellen; Ye, Rosa; Knudsen, Bjarne; Simonsen, Martin; Turner, Benjamin; de Jong, Pieter (2014-06-06).
"Efficient de novo assembly of large and complex genomes by massively parallel sequencing of Fosmid pools" . BMC Genomics . 15 (1): 439.
doi :
10.1186/1471-2164-15-439 .
PMC
4070561 .
PMID
24906298 .
^ Zhang, Hong-Bin; Scheuring, Chantel F.; Zhang, Meiping; Zhang, Yang; Wu, Cheng-Cang; Dong, Jennifer J.; Li, Yaning (2012-02-16). "Construction of BIBAC and BAC libraries from a variety of organisms for advanced genomics research". Nature Protocols . 7 (3): 479–499.
doi :
10.1038/nprot.2011.456 .
PMID
22343430 .
S2CID
205465264 .
^
a
b Ananiev, Evgueni V.; Wu, Chengcang; Chamberlin, Mark A.; Svitashev, Sergei; Schwartz, Chris; Gordon-Kamm, William; Tingey, Scott (April 2009).
"Artificial chromosome formation in maize (Zea mays L.)" . Chromosoma . 118 (2): 157–177.
doi :
10.1007/s00412-008-0191-3 .
PMID
19015867 .
^ Wu, Chengcang; Sun, Shuku; Nimmakayala, Padmavathi; Santos, Felipe A.; Meksem, Khalid; Springman, Rachael; Ding, Kejiao; Lightfoot, David A.; Zhang, Hong-Bin (February 2004).
"A BAC- and BIBAC-Based Physical Map of the Soybean Genome" . Genome Research . 14 (2): 319–326.
doi :
10.1101/gr.1405004 .
PMC
327108 .
PMID
14718376 .