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Names | |
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Preferred IUPAC name
[4-(Carbamoylamino)phenyl]arsonic acid | |
Other names
(4-Ureidophenyl)arsonic acid
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Identifiers | |
3D model (
JSmol)
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ChEMBL | |
ChemSpider | |
ECHA InfoCard | 100.004.077 |
EC Number |
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MeSH | Carbarson |
PubChem
CID
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UNII | |
CompTox Dashboard (
EPA)
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Properties | |
C7H9AsN2O4 | |
Molar mass | 260.081 g·mol−1 |
Pharmacology | |
Oral | |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Carbarsone is an organoarsenic compound used as an antiprotozoal drug for treatment of amebiasis and other infections. [1] [2] [3] It was available for amebiasis in the United States as late as 1991. Thereafter, it remained available as a turkey feed additive for increasing weight gain and controlling histomoniasis (blackhead disease). [4] [5]
Carbarsone is one of four arsenical animal drugs approved by the U.S. Food and Drug Administration for use in poultry and/or swine, along with nitarsone, arsanilic acid, and roxarsone. [6] In September 2013, the FDA announced that Zoetis and Fleming Laboratories would voluntarily withdraw current roxarsone, arsanilic acid, and carbarsone approvals, leaving only nitarsone approvals in place. [7] In 2015 FDA withdrew the approval of using nitarsone in animal feeds. The ban came into effect at the end of 2015. [8]