From Wikipedia, the free encyclopedia
Protein-coding gene in the species Homo sapiens
Centrosomal protein of 57 kDa is a
protein that in humans is encoded by the CEP57
gene .
[5]
[6] It is also known as translokin.
Translokin binds
basic fibroblast growth factor (FGF2; MIM 134920) and mediates its nuclear translocation and
mitogenic activity (Bossard et al., 2003).[supplied by OMIM]
[6]
References
^
a
b
c
GRCh38: Ensembl release 89: ENSG00000166037 –
Ensembl , May 2017
^
a
b
c
GRCm38: Ensembl release 89: ENSMUSG00000031922 –
Ensembl , May 2017
^
"Human PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^
"Mouse PubMed Reference:" . National Center for Biotechnology Information, U.S. National Library of Medicine .
^ Nagase T, Miyajima N, Tanaka A, Sazuka T, Seki N, Sato S, Tabata S, Ishikawa K, Kawarabayasi Y, Kotani H, et al. (Jul 1995).
"Prediction of the coding sequences of unidentified human genes. III. The coding sequences of 40 new genes (KIAA0081-KIAA0120) deduced by analysis of cDNA clones from human cell line KG-1" . DNA Res . 2 (1): 37–43.
doi :
10.1093/dnares/2.1.37 .
PMID
7788527 .
^
a
b
"Entrez Gene: CEP57 centrosomal protein 57kDa" .
External links
Human
CEP57 genome location and
CEP57 gene details page in the
UCSC Genome Browser .
PDBe-KB provides an overview of all the structure information available in the PDB for Human Centrosomal protein of 57 kDa
Further reading
Hoja MR, Wahlestedt C, Höög C (2000). "A visual intracellular classification strategy for uncharacterized human proteins". Exp. Cell Res . 259 (1): 239–46.
doi :
10.1006/excr.2000.4948 .
PMID
10942595 .
Nakayama M, Kikuno R, Ohara O (2003).
"Protein-protein interactions between large proteins: two-hybrid screening using a functionally classified library composed of long cDNAs" . Genome Res . 12 (11): 1773–84.
doi :
10.1101/gr.406902 .
PMC
187542 .
PMID
12421765 .
Strausberg RL, Feingold EA, Grouse LH, et al. (2003).
"Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences" . Proc. Natl. Acad. Sci. U.S.A . 99 (26): 16899–903.
Bibcode :
2002PNAS...9916899M .
doi :
10.1073/pnas.242603899 .
PMC
139241 .
PMID
12477932 .
Bossard C, Laurell H, Van den Berghe L, et al. (2003). "Translokin is an intracellular mediator of FGF-2 trafficking". Nat. Cell Biol . 5 (5): 433–9.
doi :
10.1038/ncb979 .
PMID
12717444 .
S2CID
21792653 .
Kim YS, Nakanishi G, Oudes AJ, et al. (2004).
"Tsp57: a novel gene induced during a specific stage of spermatogenesis" . Biol. Reprod . 70 (1): 106–13.
doi :
10.1095/biolreprod.103.018465 .
PMID
12954732 .
Andersen JS, Wilkinson CJ, Mayor T, et al. (2003). "Proteomic characterization of the human centrosome by protein correlation profiling". Nature . 426 (6966): 570–4.
Bibcode :
2003Natur.426..570A .
doi :
10.1038/nature02166 .
PMID
14654843 .
S2CID
4427303 .
Ota T, Suzuki Y, Nishikawa T, et al. (2004).
"Complete sequencing and characterization of 21,243 full-length human cDNAs" . Nat. Genet . 36 (1): 40–5.
doi :
10.1038/ng1285 .
PMID
14702039 .
Gerhard DS, Wagner L, Feingold EA, et al. (2004).
"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)" . Genome Res . 14 (10B): 2121–7.
doi :
10.1101/gr.2596504 .
PMC
528928 .
PMID
15489334 .
Ahn J, Chung KS, Kim DU, et al. (2005).
"Systematic identification of hepatocellular proteins interacting with NS5A of the hepatitis C virus" . J. Biochem. Mol. Biol . 37 (6): 741–8.
doi :
10.5483/bmbrep.2004.37.6.741 .
PMID
15607035 .