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American chemist
Bruce H. Lipshutz (born 1951) is an American chemist. He is a professor at the
University of California, Santa Barbara .
[1]
Biography
Lipshutz received his undergraduate degree in chemistry from
Binghamton University in 1973. His graduate work was supervised by
Harry H. Wasserman at
Yale . After a PhD degree in 1977, he spent two years at
Harvard as a post-doctoral researcher in the group of Nobel Laureate
E. J. Corey . Soon after, he accepted a position of Assistant Professor at
UCSB rising to the ranks of Professor in 1987. He has received the
Alfred P. Sloan Foundation Fellowship and the Camille & Henry Dreyfus Teacher-Scholar Award. In 2011 he was awarded Presidential Green Chemistry Award.
[2] He is Co-founder of Zymes LLC.
[3]
Contributions
Reagents
Methodologies
Higher-order organocuprates (Lipshutz cuprates).
[12]
Chiral and achiral conjugate reductions.
Catalyst development for ppm Pd-catalyzed C-C couplings in water at ambient
[13]
[14]
Use of nonionic amphiphiles for transition metal-mediated cross coupling in organic synthesis.
[15]
Low-cost synthesis of
Coenzyme Q10 .
[16]
[17]
References
^
"People | Department of Chemistry - UC Santa Barbara" . www.chem.ucsb.edu .
^
"Past Award Entries and Recipients | Green Chemistry | US EPA" . Retrieved 12 August 2023 .
^
"Zymes llc" . Archived from
the original on July 17, 2008.
^ TPGS-750-M: A Second-Generation Amphiphile for Metal-Catalyzed Cross-Couplings in Water at Room Temperature
[1]
^ “Nok”: A Phytosterol-Based Amphiphile Enabling Transition-Metal-Catalyzed Couplings in Water at Room Temperature
[2]
^ Sustainable Fe–ppm Pd nanoparticle catalysis of Suzuki-Miyaura cross-couplings in water
[3]
^ HandaPhos: A General Ligand Enabling Sustainable ppm Levels of Palladium-Catalyzed Cross-Couplings in Water at Room Temperature
[4]
^ β-(Trimethylsilyl)ethoxymethyl chloride. A new reagent for the protection of the hydroxyl group
[5]
^ Simplification of the Mitsunobu Reaction. Di-p-chlorobenzyl Azodicarboxylate: A New Azodicarboxylate
[6]
^ (BDP)CuH: A "Hot"
Stryker's reagent for Use in Achiral Conjugate Reductions
[7]
^ Asymmetric Hydrosilylation of Aryl Ketones Catalyzed by Copper Hydride Complexed by Nonracemic Biphenyl Bis-phosphine Ligands
[8]
^ Bruce H. Lipshutz, Robert Moretti, Robert Crow "Mixed Higher-order Cyanocuprate-induced Epoxide Openings: 1-Benzyloxy-4-penten-2-ol" Org. Synth. 1990, volume 69, pp. 80. {{DOI:10.15227/orgsyn.069.0080}}
^ Handa, Sachin; Andersson, Martin P.; Gallou, Fabrice; Reilly, John; Lipshutz, Bruce H. (2016).
"Handa Phos : A General Ligand Enabling Sustainable PPM Levels of Palladium-Catalyzed Cross-Couplings in Water at Room Temperature" . Angewandte Chemie International Edition . 55 (16): 4914–4918.
doi :
10.1002/anie.201510570 .
PMC
4966530 .
PMID
26924396 .
^ Landstrom, Evan B.; Handa, Sachin; Aue, Donald H.; Gallou, Fabrice; Lipshutz, Bruce H. (2018).
"Evan Phos : A ligand for PPM level Pd-catalyzed Suzuki–Miyaura couplings in either organic solvent or water" . Green Chemistry . 20 (15): 3436–3443.
doi :
10.1039/C8GC01356J .
^
"Merck KGaA" . Archived from
the original on 2016-11-12. Retrieved 2019-06-16 .
^
"NSF - OLPA - News Tip: November 29, 2002" . www.nsf.gov .
^ Lipshutz, Bruce H.; Lower, Asher; Berl, Volker; Schein, Karin; Wetterich, Frank (2005). "An Improved Synthesis of the "Miracle Nutrient" Coenzyme Q10". Organic Letters . 7 (19): 4095–4097.
doi :
10.1021/ol051329y .
PMID
16146360 .
International National Academics Other