From Wikipedia, the free encyclopedia
Benzomorphan
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Names
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IUPAC name
6,7-Benzomorphan
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Other names
- 1,2,3,4,5,6-Hexahydro-2,6-methano-3-benzazocine<
- 10-Azatricyclo[7.3.1.0~2,7~]trideca-2,4,6-triene
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Identifiers
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ChemSpider
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UNII
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InChI=1S/C12H15N/c1-2-4-12-9(3-1)7-11-8-10(12)5-6-13-11/h1-4,10-11,13H,5-8H2 NKey: NSLKFRGZLUIUKO-UHFFFAOYSA-N NInChI=1/C12H15N/c1-2-4-12-9(3-1)7-11-8-10(12)5-6-13-11/h1-4,10-11,13H,5-8H2 Key: NSLKFRGZLUIUKO-UHFFFAOYAF
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Properties
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C12H15N
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Molar mass
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173.259 g·mol−1
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Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Benzomorphan is a
chemical compound that is the base for a series of
drugs which variably act on the
sigma receptors and
κ-opioid receptors, including the following compounds:
Some of these agents are used as
analgesics, including
pentazocine,
phenazocine,
dezocine, and
eptazocine.
[1]
[2]
See also
References
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^ Kar, Ashutosh (2005).
Medicinal Chemistry - Google Books.
ISBN
9788122415650.
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^ Cittern PA, Kapoor VK, Parfitt RT (October 1986). "Preparation and analgesic activity of (−)-11 alpha-substituted 1,2,3,4,5,6-hexahydro-6 alpha,7-(methyleneoxy)-2,6-methano-3-benzazocines". Journal of Medicinal Chemistry. 29 (10): 1929–33.
doi:
10.1021/jm00160a022.
PMID
2876100.