From Wikipedia, the free encyclopedia
Barceloneic acid A
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Names
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Preferred IUPAC name
2-Hydroxy-6-[2-hydroxy-6-(hydroxymethyl)-4-methoxyphenoxy]-4-methylbenzoic acid
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Identifiers
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ChEMBL
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ChemSpider
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InChI=1S/C16H16O7/c1-8-3-11(18)14(16(20)21)13(4-8)23-15-9(7-17)5-10(22-2)6-12(15)19/h3-6,17-19H,7H2,1-2H3,(H,20,21) Key: ULPVIBVOKQAXJB-UHFFFAOYSA-N InChI=1/C16H16O7/c1-8-3-11(18)14(16(20)21)13(4-8)23-15-9(7-17)5-10(22-2)6-12(15)19/h3-6,17-19H,7H2,1-2H3,(H,20,21) Key: ULPVIBVOKQAXJB-UHFFFAOYAL
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CC1=CC(=C(C(=C1)OC2=C(C=C(C=C2CO)OC)O)C(=O)O)O
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Properties
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C16H16O7
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Molar mass
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320.294
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Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Chemical compound
Barceloneic acid A is a
farnesyl transferase inhibitor isolate of
Phoma.
[1]
References
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^ Jayasuriya, H; Ball, RG; Zink, DL; Smith, JL; Goetz, MA; Jenkins, RG; Nallin-Omstead, M; Silverman, KC; Bills, GF; Lingham, RB (1995). "Barceloneic acid A, a new farnesyl-protein transferase inhibitor from a Phoma species". Journal of Natural Products. 58 (7): 986–91.
doi:
10.1021/np50121a002.
PMID
7561907.