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Names | |
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Preferred IUPAC name
2-Amino-2-methylpropan-1-ol | |
Other names
Isobutanol-2-amine
Aminoisobutanol 2-Amino-2-methyl-1-propanol | |
Identifiers | |
3D model (
JSmol)
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ChemSpider | |
ECHA InfoCard | 100.004.282 |
PubChem
CID
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UNII | |
CompTox Dashboard (
EPA)
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Properties | |
C4H11NO | |
Molar mass | 89.138 g·mol−1 |
Density | 0.934 g/cm3 |
Melting point | 30–31 °C (86–88 °F; 303–304 K) |
Boiling point | 165.5 °C (329.9 °F; 438.6 K) |
Miscible | |
Solubility in alcohols | Soluble |
Hazards | |
Occupational safety and health (OHS/OSH): | |
Main hazards
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Irritant |
GHS labelling: [1] | |
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Warning | |
H315, H319, H412 | |
P264, P264+P265, P273, P280, P302+P352, P305+P351+P338, P321, P332+P317, P337+P317, P362+P364, P501 | |
NFPA 704 (fire diamond) | |
Except where otherwise noted, data are given for materials in their
standard state (at 25 °C [77 °F], 100 kPa).
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Aminomethyl propanol (AMP) is an organic compound with the formula H2NC(CH3)2CH2OH. It is colorless liquid that is classified as an alkanolamine. It is a useful buffer and a precursor to numerous other organic compounds. [2]
Aminomethyl propanol is typically sold as a solution of the material in water, for which different concentrations are available.
Aminomethyl propanol can be produced by the hydrogenation of 2-aminoisobutyric acid or its esters.
Aminomethyl propanol is soluble in water [3] [4] and about the same density as water. [3]
Aminomethyl propanol is used for the preparation of buffer solutions. [3] It is a component of the drugs ambuphylline and pamabrom. It is also used in cosmetics. [2]
It is a precursor to oxazolines via its reaction with acyl chlorides. [5] Via sulfation of the alcohol, the compound is also a precursor to 2,2-dimethylaziridine. [6]
Aminomethyl propanol is used as an intermediate the synthesis of fepradinol, isobucaine, and radafaxine.[ citation needed]